Tetramisole
| 매개변수 | 사양 |
|---|---|
| 제품명 | Tetramisole |
| CAS 번호 | 5086-74-8 |
| 분자식 | C11H12N2S |
| 분자량 | 204.29 g/mol |
| 외관 | 흰색에서 미백색의 결정성 분말 |
| 분석법 (HPLC) | ≥99.0% |
| 용해도 | Soluble in water, ethanol; slightly soluble in chloroform |
| 패키지 | 25 kg fiber drum with double PE liner |
도움이 필요하신가요? 저희 팀에 문의해 주세요
동의어: (±)-Tetramisole, Racemic tetramisole, 2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole, Tetramisole base, NSC 102825
Tetramisole is a synthetic imidazothiazole anthelmintic that acts as a nicotinic acetylcholine receptor agonist. Its structure features a phenyl-substituted imidazothiazole ring, which mimics the natural neurotransmitter acetylcholine and leads to sustained muscle contraction in susceptible parasites. The compound is the racemic mixture of levamisole and dextramisole, with the levo-isomer carrying the primary anthelmintic activity.
First developed in the 1960s, tetramisole is produced through a multi-step synthesis starting from styrene oxide and aminoethanethiol, followed by cyclization. It is supplied as the hydrochloride salt or the free base, with the hydrochloride form offering better water solubility. The product is typically available in technical grade for veterinary formulations and in high-purity grade for research and reference standards.
In veterinary medicine, tetramisole is used to treat gastrointestinal nematode infections in cattle, sheep, and swine. It also serves as an immunomodulator in some species and as a research tool for studying nicotinic receptor pharmacology. Its well-defined mechanism and broad-spectrum activity continue to make it a valuable ingredient in anthelmintic formulations.
Tetramisole is a white to off-white crystalline powder with a molecular weight of 204.29 g/mol. It is freely soluble in water and ethanol, making it suitable for oral drench and injectable formulations. The molecule contains a thiazole ring fused to an imidazoline ring, with a phenyl substituent at the 6-position. This lipophilic phenyl group enhances penetration through parasite cuticles. The compound is stable under normal storage conditions but should be protected from light and moisture.
| Test Item | 사양 |
|---|---|
| 식별 | IR spectrum conforms to reference standard |
| 건조 손실 | ≤0.5% |
| 소각 잔류물 | ≤0.1% |
| 중금속 | ≤20 ppm |
| 관련 물질 | Total impurities ≤1.0% |
| Microbial Limits | Total aerobic count ≤1000 CFU/g; Yeast & mold ≤100 CFU/g; E. coli absent |
Our standard MOQ is 25 kg. For smaller quantities, please contact us to discuss your specific needs.
For stock items, delivery is 3-5 business days after order confirmation.
Yes, we provide a COA for each batch. Samples are available upon request; please contact our sales team for arrangements.
send us your specification for a quotation.
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