Dapoxetine

Dapoxetine

パラメータ 仕様
製品名 Dapoxetine
CAS番号 119356-77-3
分子式 C21H23NO
分子量 305.41 g/mol
外観 白色からオフホワイトの結晶性粉末
分析(HPLC) ≥99.0%
溶解度 Soluble in methanol, ethanol; slightly soluble in water
パッケージ 25 kg net weight in fiber drums, two polyethylene inner liners

Dapoxetine Structure

同義語: Dapoxetine hydrochloride, (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine, LY210448, Priligy

Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) developed specifically for the treatment of premature ejaculation (PE). Unlike other SSRIs, dapoxetine has a rapid onset and short half-life, making it suitable for on-demand dosing. It is the first oral medication approved for PE in several countries and has gained significant attention in the pharmaceutical market.

Dapoxetine is synthesized through a multi-step chemical process, yielding a highly pure active pharmaceutical ingredient (API). It is available as the hydrochloride salt, which enhances its solubility and stability. The compound is typically manufactured under cGMP conditions to ensure consistent quality and compliance with pharmacopeial standards.

製品の概要と成分

Dapoxetine is a chiral molecule with the (S)-configuration at the stereogenic center. It acts by inhibiting the reuptake of serotonin, thereby increasing serotonin levels in the synaptic cleft and delaying ejaculation. The hydrochloride salt is the predominant form used in commercial products due to its favorable physicochemical properties.

The API is characterized by high purity, typically ≥99.0% as determined by HPLC, and low levels of organic impurities. It is a white to off-white crystalline powder, freely soluble in methanol and ethanol, and slightly soluble in water.

Applications & Product Lines

  • Pharmaceutical formulations: Dapoxetine is formulated into immediate-release tablets for the treatment of premature ejaculation.
  • Research and development: Used as a reference standard in analytical laboratories and for studying serotonin reuptake inhibition.
  • Generic drug manufacturing: API for generic versions of dapoxetine hydrochloride tablets.
  • Contract manufacturing: Supplied to CDMOs for incorporation into finished dosage forms.

Quality Control Standards

Test Item 仕様
識別 IR spectrum complies with reference standard
乾燥減量 ≤0.5%
重金属 ≤20 ppm
Organic Impurities Any individual ≤0.1%; total ≤0.5%
Microbial Limits Total aerobic microbial count ≤1000 CFU/g; yeast and mold ≤100 CFU/g; absence of E. coli

Bulk Packaging & Supply

  • パッケージ: 25 kg fiber drums with two polyethylene inner liners
  • 最小注文数量(MOQ): 1 kg
  • リードタイム: 3-5 business days for stock items
  • ドキュメント: COA, MSDS, TDS available upon request

よくある質問

What is the minimum order quantity (MOQ) for Dapoxetine?

Our MOQ is 1 kg. For larger quantities, please contact us for pricing and availability.

What is the delivery time?

For stock items, delivery is typically 3-5 business days after order confirmation.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, we provide a COA for each batch. Samples are available upon request.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

send us your specification for a quotation.

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Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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