Ferrous fumarate

Synonyms: Iron(II) fumarate, Ferrous fumarate, Iron fumarate, Ferrous iron fumarate, Fumaric acid iron(II) salt, (E)-2-Butenedioic acid iron(II) salt

Ferrous fumarate has become a go-to iron source for formulators seeking a well-tolerated, high-elemental-iron alternative to ferrous sulfate. As the global demand for iron supplementation continues to rise—driven by widespread iron-deficiency anemia and growing awareness of maternal and pediatric nutrition—ferrous fumarate stands out for its favorable gastrointestinal profile and excellent stability in solid dosage forms.

Chemically, ferrous fumarate is the iron(II) salt of fumaric acid, with the formula C4H2FeO4. It is produced by reacting ferrous sulfate with sodium fumarate, yielding a reddish-orange, finely divided powder that is practically insoluble in water but readily soluble in dilute mineral acids. This low solubility contributes to its gentle effect on the stomach compared to more soluble iron salts.

Our ferrous fumarate is standardized to contain 31.0%–36.0% elemental iron, meeting the stringent requirements of the USP/EP/BP monographs. It is available in a free-flowing powder form suitable for direct compression, capsule filling, and suspension formulations. Each batch is tested for iron content, loss on drying, and heavy metals to ensure consistent performance in your finished product.

製品の概要と成分

Ferrous fumarate is a coordination compound in which iron is in the +2 oxidation state, chelated by fumarate ions. The fumarate ligand not only stabilizes the ferrous ion but also contributes to the molecule’s overall stability, making it less prone to oxidation than ferrous sulfate. The compound is essentially odorless and has a slightly astringent taste.

In the body, ferrous fumarate dissociates in the acidic environment of the stomach, releasing ferrous iron for absorption in the duodenum. The fumarate moiety is metabolized via the Krebs cycle, leaving no harmful residues. This efficient delivery system allows for a high bioavailability of iron, often comparable to that of ferrous sulfate, but with a lower incidence of gastric irritation.

主な用途

• Dietary supplements: Tablets, capsules, and chewables for iron supplementation in adults and children.
• Pharmaceutical preparations: Prescription and OTC iron therapies for the treatment and prevention of iron-deficiency anemia.
• Pediatric and prenatal nutrition: Gentle iron source suitable for prenatal vitamins and pediatric drops.
• Food fortification: Added to cereals, infant formula, and other staple foods to combat iron deficiency.
• Veterinary use: Iron supplementation for livestock and pets.

品質と基準

包装・供給

• パッケージ: 25 kg fiber drums with double polyethylene liners, or as per customer requirements.
• 最小注文数量（MOQ）: 500 kg.
• リードタイム: 3～5営業日（在庫品）
• ドキュメント: COA, MSDS, TDS, and regulatory support available upon request.

見積依頼

• リブバイオ株式会社. — メールアドレス： info@lyvbio.com