| 製品名 | ヒドロキシアパタイト |
|---|---|
| CAS番号 | 1306-06-5 |
| 分子式 | Ca₅(PO₄)₃(OH) |
| 分子量 | 502.31 g/mol |
| 外観 | White to off-white fine powder |
| Particle size | 40um, 40-60nm |
| Assay (as Ca₅(PO₄)₃(OH)) | ≥ 99.99% |
| 乾燥減量 | ≤ 1.0% |
| 焼失残渣 | ≤ 0.1% |
| 重金属 | 10 ppm以下 |
| 粒子径 | Nanoparticle (<100 nm),
micron (1–100 µm), or custom |
| ストレージ | Store in a cool, dry place, sealed |
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同義語： Hydroxyapatite, HA, HAp, Calcium Hydroxyapatite, Calcium Phosphate Hydroxide, Hydroxylapatite, Durapatite, Bone Mineral, Calcium Apatite
Hydroxyapatite (HA or HAp) is a naturally occurring mineral form of calcium apatite and the primary inorganic component of human bone and tooth enamel. It accounts for approximately 60–70% of bone mass and 95–99% of enamel, making it one of the most important biomaterials in medical and dental applications.
Synthetic hydroxyapatite is chemically identical to biological hydroxyapatite and is biocompatible, osteoconductive, and non‑toxic. Its structure allows for strong bonding with bone tissue, making it an ideal material for bone regeneration, dental implants, and drug delivery systems.
In cosmetic and personal care applications, hydroxyapatite is used as a gentle abrasive in toothpaste and as a remineralizing agent to repair early enamel lesions. Its nanoparticle form is also being explored for targeted drug delivery and diagnostic imaging.
CALCIUM PHOSPHATE
Bone regeneration: Supports osteoconduction and new bone formation.
Dental remineralization: Restores enamel integrity and reduces sensitivity.
Biocompatibility: Excellent integration with host tissue.
Drug delivery carrier: Sustained release of pharmaceuticals.
Gentle abrasive: Used in oral care products for cleaning without enamel damage.
Cosmetic applications: Skin conditioning and mineral absorption.
出典: Synthetic (wet chemical precipitation, sol‑gel, or hydrothermal methods) or natural (bovine, marine, or eggshell-derived)
標準化: ≥99.99% hydroxyapatite (as Ca₅(PO₄)₃(OH))
Ca/P Molar Ratio: 1.67 ± 0.02 (stoichiometric)
| Grade | 純度 | 粒子径 | 用途 |
|---|---|---|---|
| Medical Grade | ≥99.99% | Nanoparticles to microns | Bone grafts, coatings, implants |
| Dental Grade | ≥99.0% | Micron | Toothpaste, remineralization |
| Cosmetic Grade | ≥98.0% | Nanoparticles | Skincare, anti‑aging |
| Research Grade | ≥99.99% | Custom | Drug delivery, cell culture |
| 適用分野 | Typical Concentration / Usage | 根拠 |
|---|---|---|
| Bone grafts / Orthopedics | Implant coating, scaffold | Osteoconduction, biointegration |
| Dental care / Toothpaste | 5 – 20% | Remineralization, gentle abrasion |
| Skincare / Cosmetic | 0.5 – 5.0% | Mineral delivery, skin conditioning |
| Drug delivery | 変数 | Controlled release of therapeutics |
| Research / Cell culture | 変数 | Scaffold for stem cell culture |
| パラメータ | 仕様 |
|---|---|
| Hydroxyapatite Content (as Ca₅(PO₄)₃(OH)) | ≥ 99.99% |
| Particle size | 40um , 40-60nm |
| Calcium Content | 38.5 – 40.0% |
| Phosphorus Content | 17.5 – 18.5% |
| Ca/P Molar Ratio | 1.67 ± 0.02 |
| 重金属（鉛換算） | 10 ppm以下 |
| ヒ素（As） | 1 ppm以下 |
| Fluoride (F) | ≤ 0.005% |
| 乾燥減量 | ≤ 1.0% |
| 焼失残渣 | ≤ 0.1% |
| 微生物の許容限度 | USP/EP規格に準拠しています |
月間処理能力: 500+ kg (bulk), 50+ kg (high‑purity research grade)
リードタイム: 3～5日（サンプル）、10～15日（バルク）
ドキュメント: COA, MSDS, TDS, XRD pattern, particle size analysis, stability data (upon request)
パッケージ: 1 kg、5 kg、10 kg、25 kg
中国陝西省西安市メインストリート280番地
リブバイオ株式会社.
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