Deoxycholic Acid

Deoxycholic Acid

製品名 Deoxycholic Acid
CAS番号 83-44-3
分子式 C24H40O4
分子量 392.57 g/mol
外観 白色からオフホワイトの結晶性粉末
分析(HPLC) ≥99.0%
融点 174-176 °C
比回転 [α]D20 +55° (c=1, ethanol)
乾燥減量 ≤0.5%
焼失残渣 ≤0.11 TP3T
重金属 10 ppm以下
溶解度 Soluble in ethanol, methanol, acetone; slightly soluble in water
パッケージ 25 kg fiber drum with double polyethylene liner

Deoxycholic Acid Structure

同義語: 3α,12α-Dihydroxy-5β-cholan-24-oic acid; 7-Deoxycholic acid; Cholanoic acid; 5β-Cholan-24-oic acid, 3α,12α-dihydroxy-; Deoxycholate; DCA

Deoxycholic acid has moved from a niche bile acid to a mainstream ingredient in both pharmaceutical and cosmetic formulations. Its unique ability to solubilize fats and disrupt cell membranes has made it a key component in injectable fat-reduction treatments, while formulators value it as a natural emulsifier and penetration enhancer. The global demand for high-purity deoxycholic acid is rising, particularly in the pharmaceutical and personal care sectors, where consistent quality and regulatory compliance are non-negotiable.

Chemically, deoxycholic acid is a secondary bile acid produced in the colon by bacterial 7α-dehydroxylation of cholic acid. It is a white to off-white crystalline powder with a molecular formula of C24H40O4 and a molecular weight of 392.57 g/mol. While it occurs naturally in human bile, commercial production relies on controlled synthesis or semi-synthesis from cholic acid, ensuring a reliable supply chain for industrial users.

LyvBio supplies deoxycholic acid with a minimum assay of 99.0% (HPLC), meeting the stringent requirements of pharmaceutical and cosmetic applications. Our material is manufactured under cGMP conditions and undergoes rigorous quality control, including tests for heavy metals, residual solvents, and microbial limits. Whether you are developing a new injectable formulation or a topical fat-dissolving product, our deoxycholic acid offers the purity and consistency you need.

製品の概要と成分

Deoxycholic acid is a steroid acid, belonging to the class of dihydroxy bile acids. Its structure features a steroid nucleus with hydroxyl groups at positions 3α and 12α, and a carboxyl side chain. This amphiphilic nature allows it to form micelles and emulsify lipids, a property that is exploited in various applications.

Our deoxycholic acid is synthesized from high-quality cholic acid through a multi-step process that includes selective dehydroxylation and purification. The final product is a single, well-characterized compound, not a mixture. Each batch is tested for identity, purity, and residual solvents to ensure compliance with EP, USP, and other pharmacopeial standards.

主な用途

  • Injectable fat reduction: Used as the active ingredient in deoxycholic acid injections for the treatment of submental fat (double chin). It works by dissolving fat cell membranes, leading to cell lysis and subsequent fat clearance.
  • Pharmaceutical formulations: Acts as a solubilizing agent for poorly water-soluble drugs, enhancing their bioavailability. Also used in bile acid replacement therapies.
  • Cosmetic and personal care: Incorporated into topical slimming and anti-cellulite products due to its lipolytic properties. It also serves as an emulsifier in creams and lotions.
  • Research and diagnostics: Employed in studies of bile acid metabolism, liver function, and as a reference standard in analytical laboratories.
  • Chemical synthesis: Used as a chiral building block for the synthesis of steroids and other complex molecules.

品質と基準

パラメータ 仕様
分析(HPLC) ≥99.0%
乾燥減量 ≤0.5%
焼失残渣 ≤0.11 TP3T
重金属 10 ppm以下
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent
残留溶剤 Meets EP/USP requirements

包装・供給

  • パッケージ: 25 kg fiber drum with double polyethylene liner, or as per customer request.
  • 最小注文数量(MOQ): 1 kg for trial orders, 25 kg for commercial orders.
  • リードタイム: 3~5営業日(在庫品)
  • ドキュメント: COA, MSDS, TDS, and regulatory support available upon request.
  • ストレージ: Store in a cool, dry place, away from direct sunlight. Keep container tightly closed.

見積依頼

  • リブバイオ株式会社. — メールアドレス: info@lyvbio.com

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