Veratrum Alkaloids

Sinonimi: Veratrum Alkaloids, Veratridine, Cevadine, Veracevine, 3-Veratroylveracevine, (3β,4α,16β)-4,9-Epoxycevane-3,4,12,14,16,17,20-heptol 3-(3,4-dimethoxybenzoate), Cevane-3,4,12,14,16,17,20-heptol 3-(3,4-dimethoxybenzoate)

Veratrum alkaloids have become a sought-after class of steroidal alkaloids for companies developing ion-channel modulators, neuropharmacology tools, and cardiovascular research reagents. Their ability to lock voltage-gated sodium channels in the open state gives them a distinct profile among natural products, and demand has grown steadily from both API manufacturers and life-science suppliers.

The alkaloids are extracted from the rhizomes and roots of Veratrum album and Veratrum viride, plants long known in traditional medicine but now valued for their precise chemical activity. The main constituents are veratridine, cevadine, and related cevane-type esters, which share a common steroidal skeleton with varying ester side chains.

LyvBio supplies Veratrum Alkaloids standardized to ≥98% total alkaloids by HPLC, a grade suited to reference-standard preparation, electrophysiology assays, and early-stage formulation work. Each lot is profiled for individual alkaloid ratios so buyers can match the material to their intended mechanism of study.

Product Overview & Composition

This product is a concentrated alkaloid fraction rather than a single molecule. Veratridine typically dominates, accompanied by cevadine and smaller amounts of veracevine derivatives. The exact ratio depends on the botanical source and harvest, so we provide a chromatographic profile with every batch.

The compounds act on neurotoxin receptor site 2 of voltage-gated sodium channels, delaying inactivation and prolonging the open state. That mechanism underlies their use as pharmacological probes and as starting points for synthetic analogs.

Applications & Product Lines

• Ion-channel research: Standard tool for studying sodium channel gating and neurotoxicity pathways.
• Reference standards: Suitable for HPLC and LC-MS method development where veratridine or cevadine is the target analyte.
• Pharmaceutical intermediates: Used in the synthesis of steroidal alkaloid derivatives for cardiovascular and neurological studies.
• Agrochemical screening: Evaluated as a bio-based insecticidal lead against resistant pest strains.
• Analytical testing: Employed by contract labs to validate alkaloid detection in plant matrices.

Quality Control Standards

Bulk Packaging & Supply

• Confezionamento: 25 kg fiber drum with double PE liner; 1 kg foil bag for sample orders.
• MOQ: 1 kg for stock items; 25 kg for custom packing.
• Tempi di consegna: 3-5 business days from order confirmation.
• Documentazione: COA, MSDS, TDS, and chromatographic profile issued per lot.

Frequently Asked Questions

What is the MOQ for Veratrum Alkaloids?

We keep 1 kg foil bags in stock, so the minimum order is 1 kg. Larger quantities in 25 kg drums are available from the same batch.

How long does delivery take?

Stock items ship within 3-5 business days after order confirmation. We dispatch from our warehouse and provide tracking details the same day.

Can you provide a COA and sample?

Yes. A lot-specific COA with HPLC data is sent before shipment. Samples of 10-50 g are available for evaluation and usually ship within 1-2 days.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.