Gliclazide

Gliclazide

Nome del prodotto Gliclazide
Numero CAS 21187-98-4
Formula molecolare C15H21N3O3S
Peso molecolare 323.41 g/mol
Aspetto White or almost white crystalline powder
Analisi (HPLC) 98.0% - 102.0%
Perdita per essiccazione ≤ 0,51 TP3T
Residuo di combustione ≤ 0,11 TP3T
Metalli pesanti ≤ 10 ppm
Punto di fusione 163°C - 169°C
Rotazione specifica Not applicable (racemic mixture)

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Gliclazide Structure

Sinonimi

  • Gliclazide, Diamicron, Glimicron, Diabezide, Glizide, Glyclazide, 1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-(4-methylphenylsulfonyl)urea

Gliclazide has been a cornerstone in type 2 diabetes management for decades, and it’s still widely prescribed today — because it works. As a second-generation sulfonylurea, it stimulates insulin release from pancreatic beta cells, helping patients lower blood glucose without the extreme peaks and troughs seen with some older agents. What sets gliclazide apart is its unique azabicyclo-octyl ring, which gives it a favorable safety profile, particularly for cardiovascular outcomes. That’s why it remains a trusted choice in many national formularies, especially in Europe and Asia.

For manufacturers and formulators, gliclazide offers a reliable, well-documented API with predictable pharmacokinetics and a proven track record. We supply gliclazide as a high-purity crystalline powder, every batch meeting strict pharmacopoeial standards and shipped with a full COA. Whether you need a 1 kg sample for R&D or a full container load for commercial production, we’ve got the flexibility and logistics to keep your supply chain moving.

Funzione

  • Insulin secretagogue: Binds to sulfonylurea receptors on pancreatic beta cells, closing ATP-sensitive potassium channels and triggering calcium influx — leading to rapid, glucose-dependent insulin release.
  • Glycemic control: Effectively lowers HbA1c levels, with a once-daily dosing regimen that improves patient compliance compared to multiple-dose sulfonylureas.
  • Cardiovascular safety: Gliclazide has been shown to have neutral or beneficial effects on the cardiovascular system, unlike some older sulfonylureas; it also reduces oxidative stress and platelet aggregation, adding a layer of protection for diabetic patients.

Documentazione e forniture

  • Documentazione: COA, SDS, TDS
  • Tempi di consegna: 5-10 days for standard orders, with expedited options available
  • Imballaggio: Double-layer polyethylene bags inside fiber drums, 25 kg per drum, or custom packing per request

Richiesta di preventivo

  • Il nostro indirizzo: 280 Main Street, Xian, Shaanxi, Cina
  • LyvBio S.r.l. — E-mail: info@lyvbio.com

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