Curcumina

Curcumina

Nome del prodotto Curcumina
Numero CAS 458-37-7
Formula molecolare C₂₁H₂₀O₆
Peso molecolare 368.38 g/mol
Aspetto Polvere cristallina di colore da giallo ad arancione
Analisi (HPLC) Natural: ≥ 95.0%; Synthetic: ≥ 98.0%
Perdita per essiccazione ≤ 1,01 TP3T
Residuo di combustione ≤ 0,51 TP3T
Metalli pesanti ≤ 10 ppm
Punto di fusione 176 – 180°C
Dimensione delle particelle Da 100% a 80 mesh

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Sinonimi: Curcumin, Diferuloylmethane, (1E,6E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione, Turmeric Yellow, Natural Yellow 3, C.I. 75300

Curcumin is the principal bioactive polyphenol found in turmeric (Curcuma longa L.), the rhizome of a plant native to Southeast Asia. It is responsible for turmeric’s characteristic yellow color and has been used for centuries in traditional medicine, culinary applications, and as a natural dye. It is a member of the curcuminoid family, along with demethoxycurcumin and bisdemethoxycurcumin.

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Curcumin, CAS 458-37-7

Curcumin has been extensively studied for its wide range of biological activities, including antioxidant, anti-inflammatory, antimicrobial, and anticancer properties. Its mechanism of action involves modulation of multiple molecular targets, including NF-κB, COX-2, TNF-α, and various kinases. Curcumin is one of the most thoroughly investigated natural compounds, with thousands of scientific publications supporting its health benefits.

Curcumin is available in both natural (extracted from turmeric) and synthetic forms. Natural curcumin is a mixture of curcuminoids (typically containing 95% total curcuminoids). Synthetic curcumin is chemically identical to natural curcumin but offers higher purity (≥98%) and is free from the variability of botanical sources, making it suitable for research and pharmaceutical applications where consistent composition is critical.

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Funzione

  • Attività antiossidante: Scavenges free radicals, upregulates endogenous antioxidant enzymes (SOD, CAT, GPx).

  • Attività antinfiammatoria: Inhibits COX-2, LOX, and suppresses NF-κB pathway.

  • Attività antimicrobica: Broad-spectrum activity against bacteria, fungi, and viruses.

  • Neuroprotective effects: Supports cognitive function and neuronal health.

  • Supporto cardiovascolare: Modulates lipid metabolism and endothelial function.

  • Joint health: Supports joint comfort and mobility.

Caratteristiche tecniche

Parametro Natural Curcumin 95% Synthetic Curcumin 98%
Curcumin Content (HPLC) ≥95.0% (total curcuminoids) ≥98.0%
Identificazione UV / IR conforms UV / IR / MS / NMR conforms
Perdita per essiccazione ≤ 1,01 TP3T ≤ 0,51 TP3T
Residuo di combustione ≤ 0,51 TP3T ≤ 0,11 TP3T
Metalli pesanti ≤ 10 ppm ≤ 10 ppm
Solventi residui Meets USP Meets USP

Documentazione e forniture

  • Capacità mensile: Natural 95%: 5,000+ kg; Synthetic 98%: 500+ kg

  • Tempi di consegna: 3–5 giorni (campioni), 10–15 giorni (carichi)

  • Documentazione: COA, SDS, TDS

  • Imballaggio: 1 kg, 5 kg, 10 kg, 25 kg

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