Arginine Ferulate

Arginine Ferulate

Nome del prodotto Arginine Ferulate
Numero CAS 950890-74-1
Synonyms L-Arginine Ferulate, Arginine Ferulic Acid Salt, Feruloyl Arginine
Aspetto Polvere cristallina di colore da bianco a bianco sporco
Formula molecolare C16H24N4O5
Peso molecolare 352.39 g/mol
Analisi (HPLC) ≥98.0%
Solubilità Soluble in water, ethanol; slightly soluble in acetone
Metalli pesanti ≤10 ppm
Confezione 25 kg net weight in fiber drum with double polyethylene liner

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Arginine Ferulate Structure

Sinonimi: L-Arginine Ferulate, Arginine Ferulic Acid Salt, Feruloyl Arginine, (S)-2-Amino-5-guanidinopentanoic acid ferulate

Arginine Ferulate is a molecular salt formed between the amino acid L-arginine and ferulic acid, a naturally occurring phenolic compound found in plant cell walls. This hybrid molecule combines the nitric oxide-boosting properties of arginine with the potent antioxidant activity of ferulic acid, creating a synergistic ingredient that has garnered interest in both pharmaceutical and nutraceutical applications. Unlike simple physical mixtures, the salt formation enhances the stability and bioavailability of both components, making it a preferred choice for formulations requiring precise dosing and consistent performance.

Ferulic acid, chemically known as 4-hydroxy-3-methoxycinnamic acid, is abundant in rice bran, wheat germ, and certain fruits and vegetables. It is renowned for its ability to neutralize free radicals and protect against oxidative stress. When ionically bonded to L-arginine, the resulting compound exhibits improved water solubility and a neutral pH in solution, which is particularly advantageous for injectable and topical formulations. The arginine moiety serves not only as a counterion but also contributes its own physiological benefits, including support for cardiovascular health and immune function.

In the B2B arena, Arginine Ferulate is supplied as a high-purity crystalline powder, typically with an assay of ≥98% as determined by HPLC. It finds use as an active pharmaceutical ingredient (API) in cardiovascular and neuroprotective drugs, as well as a functional ingredient in dietary supplements targeting blood flow and antioxidant defense. Its dual-action mechanism makes it a valuable component in products designed for metabolic support, skin health, and anti-aging.

Manufacturers and formulators appreciate Arginine Ferulate for its excellent stability profile and compatibility with a wide range of excipients. The compound is non-hygroscopic and maintains its integrity under normal storage conditions, ensuring a long shelf life. With growing consumer demand for multi-functional ingredients, this salt offers a convenient way to deliver two complementary bioactives in a single, well-characterized molecule.

Funzione

  • Nitric oxide precursor: L-arginine serves as a substrate for nitric oxide synthase, supporting vasodilation and healthy circulation.
  • Antioxidant activity: Ferulic acid scavenges free radicals and upregulates endogenous antioxidant enzymes.
  • Endothelial support: The combination helps maintain endothelial function and vascular tone.
  • Anti-inflammatory effects: Modulates inflammatory pathways, potentially reducing cytokine production.
  • Skin protection: Ferulic acid provides photoprotection and combats oxidative damage in dermal formulations.
  • Metabolic health: Supports glucose metabolism and insulin sensitivity in preclinical models.

Fonte e standardizzazione

  • Fonte: Synthetic conjugation of L-arginine (fermentation-derived) and ferulic acid (plant-derived, typically from rice bran or corn)
  • Extraction: Ferulic acid is extracted from plant sources and purified; L-arginine is produced via microbial fermentation; the salt is formed through controlled neutralization.
  • Standardizzazione: ≥98.0% Arginine Ferulate (HPLC)
  • Moduli: White to off-white crystalline powder
  • Applicazioni: Pharmaceuticals, nutraceuticals, functional foods, cosmeceuticals, research

Caratteristiche tecniche

Parametro Specifiche
Analisi (HPLC) ≥98.0%
Identificazione IR, HPLC retention time conforms to standard
Perdita per essiccazione ≤0.5%
Residuo di combustione ≤0.1%
Metalli pesanti ≤10 ppm
Limiti microbiologici Conta aerobica totale ≤ 1000 UFC/g; lieviti e muffe ≤ 100 UFC/g; assenza di E. coli
Particle Size 100% pass through 80 mesh

Documentazione e forniture

  • Capacità mensile: 5 tonnellate metriche
  • Tempi di consegna: 3-5 business days (stock items)
  • Documentazione: COA, MSDS, TDS, stability data, regulatory support (DMF available upon request)
  • Confezionamento: 25 kg fiber drums with double polyethylene liners; custom packaging available

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