Copper Tripeptide-1 (GHK-Cu)

Copper Tripeptide-1 (GHK-Cu)

Nome del prodotto Copper Tripeptide-1 (GHK-Cu)
Numero CAS 89030-95-5
Formula molecolare C14H22CuN6O4
Peso molecolare 402.92 g/mol
Aspetto Blue to violet-blue crystalline powder
Analisi (HPLC) ≥98.0%
Solubilità Soluble in water (up to 10 mg/mL), slightly soluble in ethanol
Perdita per essiccazione ≤5.0%
Metalli pesanti ≤10 ppm
Archiviazione Store at -20°C, protected from light and moisture
Confezione 1 g, 5 g, 10 g, 50 g, 100 g in amber glass vials or as requested

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Copper Tripeptide-1 (GHK-Cu) Structure

Sinonimi: GHK-Cu, Copper Peptide-1, Copper Tripeptide-1, Glycyl-L-histidyl-L-lysine copper complex, Copper Glycyl-Histidyl-Lysine, GHK Copper

Copper Tripeptide-1, also known as GHK-Cu, is a synthetic tripeptide complexed with copper(II) ions. Its sequence—glycyl-L-histidyl-L-lysine—was first isolated from human plasma and later identified as a natural component of wound healing and tissue remodeling processes. The copper ion is chelated by the histidine imidazole and the α-amino group of the peptide, giving the molecule its characteristic blue color and distinct biochemical activity.

As a cosmetic and pharmaceutical ingredient, GHK-Cu has gained significant traction in anti-aging, skin repair, and hair growth formulations. It is also a subject of ongoing research in regenerative medicine, where its ability to modulate collagen synthesis, angiogenesis, and inflammatory pathways is being explored. The material is typically supplied as a high-purity synthetic peptide with a copper content of approximately 15-16% (w/w), ensuring consistent performance in topical and injectable applications.

 

Funzione

  • Collagen and elastin stimulation: Upregulates collagen I, III, and elastin production in fibroblasts, improving skin firmness and elasticity.
  • Antioxidant and anti-inflammatory: Copper ions scavenge free radicals and modulate inflammatory cytokines, reducing oxidative stress in tissues.
  • Wound healing and tissue repair: Promotes angiogenesis and extracellular matrix remodeling, accelerating repair processes.
  • Hair growth support: Enhances follicle size and hair shaft thickness by stimulating dermal papilla cells.
  • Copper delivery: Acts as a safe, bioavailable copper carrier for enzymatic and cellular functions.

Fonte e standardizzazione

  • Fonte: Synthetic solid-phase peptide synthesis
  • Complexation: Copper(II) chloride or copper(II) acetate used to form the chelate
  • Purification: HPLC purification to ≥98% purity
  • Standardizzazione: Copper content 15.5-16.5% (w/w) by ICP-MS or atomic absorption
  • Moduli: Blue to violet-blue crystalline powder
  • Applicazioni: Cosmeceuticals, wound care, hair care, research

Caratteristiche tecniche

Parametro Specifiche
Aspetto Blue to violet-blue crystalline powder
Analisi (HPLC) ≥98.0%
Copper Content 15.5-16.5%
Water Content ≤5.0%
Metalli pesanti ≤10 ppm
Solubilità Soluble in water, slightly soluble in ethanol
Archiviazione -20°C, protected from light

Documentazione e forniture

  • Confezionamento: 1 g, 5 g, 10 g, 50 g, 100 g in amber glass vials; custom packaging available.
  • MOQ: 1 g for standard packs; 10 g for bulk orders.
  • Tempi di consegna: 3-5 business days for in-stock items; 2-3 weeks for custom synthesis.
  • Documentazione: COA, MSDS, TDS provided with each shipment.
  • Archiviazione: Store at -20°C, protected from light and moisture.

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