Deoxycholic Acid

Sinonimi: 3α,12α-Dihydroxy-5β-cholan-24-oic acid; 7-Deoxycholic acid; Cholanoic acid; 5β-Cholan-24-oic acid, 3α,12α-dihydroxy-; Deoxycholate; DCA

Deoxycholic acid has moved from a niche bile acid to a mainstream ingredient in both pharmaceutical and cosmetic formulations. Its unique ability to solubilize fats and disrupt cell membranes has made it a key component in injectable fat-reduction treatments, while formulators value it as a natural emulsifier and penetration enhancer. The global demand for high-purity deoxycholic acid is rising, particularly in the pharmaceutical and personal care sectors, where consistent quality and regulatory compliance are non-negotiable.

Chemically, deoxycholic acid is a secondary bile acid produced in the colon by bacterial 7α-dehydroxylation of cholic acid. It is a white to off-white crystalline powder with a molecular formula of C24H40O4 and a molecular weight of 392.57 g/mol. While it occurs naturally in human bile, commercial production relies on controlled synthesis or semi-synthesis from cholic acid, ensuring a reliable supply chain for industrial users.

LyvBio supplies deoxycholic acid with a minimum assay of 99.0% (HPLC), meeting the stringent requirements of pharmaceutical and cosmetic applications. Our material is manufactured under cGMP conditions and undergoes rigorous quality control, including tests for heavy metals, residual solvents, and microbial limits. Whether you are developing a new injectable formulation or a topical fat-dissolving product, our deoxycholic acid offers the purity and consistency you need.

Product Overview & Composition

Deoxycholic acid is a steroid acid, belonging to the class of dihydroxy bile acids. Its structure features a steroid nucleus with hydroxyl groups at positions 3α and 12α, and a carboxyl side chain. This amphiphilic nature allows it to form micelles and emulsify lipids, a property that is exploited in various applications.

Our deoxycholic acid is synthesized from high-quality cholic acid through a multi-step process that includes selective dehydroxylation and purification. The final product is a single, well-characterized compound, not a mixture. Each batch is tested for identity, purity, and residual solvents to ensure compliance with EP, USP, and other pharmacopeial standards.

Key Applications

• Injectable fat reduction: Used as the active ingredient in deoxycholic acid injections for the treatment of submental fat (double chin). It works by dissolving fat cell membranes, leading to cell lysis and subsequent fat clearance.
• Pharmaceutical formulations: Acts as a solubilizing agent for poorly water-soluble drugs, enhancing their bioavailability. Also used in bile acid replacement therapies.
• Cosmetic and personal care: Incorporated into topical slimming and anti-cellulite products due to its lipolytic properties. It also serves as an emulsifier in creams and lotions.
• Research and diagnostics: Employed in studies of bile acid metabolism, liver function, and as a reference standard in analytical laboratories.
• Chemical synthesis: Used as a chiral building block for the synthesis of steroids and other complex molecules.

Quality & Standards

Packaging & Supply

• Confezionamento: 25 kg fiber drum with double polyethylene liner, or as per customer request.
• MOQ: 1 kg for trial orders, 25 kg for commercial orders.
• Tempi di consegna: 3-5 business days (stock items)
• Documentazione: COA, MSDS, TDS e documentazione normativa disponibili su richiesta
• Archiviazione: Store in a cool, dry place, away from direct sunlight. Keep container tightly closed.

Richiesta di preventivo

• LyvBio S.r.l. — E-mail: info@lyvbio.com