Thiamine nitrate
| Nom du produit | Thiamine nitrate |
|---|---|
| Autres noms | Vitamin B1 nitrate, Thiamine mononitrate, Aneurine nitrate |
| Numéro CAS | 532-43-4 |
| Formule moléculaire | C12H17N5O4S |
| Poids moléculaire | 327.36 g/mol |
| Apparence | Poudre cristalline blanche à blanc cassé |
| Assay | 98.0% – 101.0% (on dried basis) |
| Perte au séchage | ≤ 1,01 TP3T |
| Résidu au feu | ≤ 0,11 TP3T |
| pH (2% solution) | 6.5 – 7.5 |
| Métaux lourds | ≤ 10 ppm |
| Solubilité | Soluble in water (~1 g/10 mL), slightly soluble in ethanol |
| Colis | Fût en fibre de 25 kg avec double revêtement en polyéthylène |
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Synonyms: Thiamine mononitrate, Vitamin B1 nitrate, Aneurine nitrate, 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium nitrate
Thiamine nitrate is the nitrate salt form of thiamine (vitamin B1), a water-soluble vitamin essential for carbohydrate metabolism and neural function. It is produced synthetically and supplied as a white to off-white crystalline powder with a characteristic faint odor. Unlike thiamine hydrochloride, the nitrate salt is less hygroscopic and exhibits greater stability in dry blends, making it a preferred choice for certain solid dosage forms and food fortification.
As a vitamin B1 source, thiamine nitrate is widely used in pharmaceutical preparations, dietary supplements, and food enrichment. It plays a critical role in energy production as a coenzyme in the citric acid cycle and pentose phosphate pathway. The nitrate form is particularly valued in multivitamin tablets and premixes where moisture sensitivity is a concern.
| Paramètre | Spécifications |
|---|---|
| Assay (on dried basis) | 98.0% – 101.0% |
| Perte au séchage | ≤ 1,01 TP3T |
| Résidu au feu | ≤ 0,11 TP3T |
| pH (2% solution) | 6.5 – 7.5 |
| Métaux lourds | ≤ 10 ppm |
| Apparence | Poudre cristalline blanche à blanc cassé |
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