Alpha-arbutine

Synonymes : 4-Hydroxyphenyl α-D-glucopyranoside, Hydroquinone α-D-glucoside, Alpha-Arbutin, α-Arbutin

Alpha-Arbutin is a hydroquinone derivative with a sugar moiety, specifically 4-hydroxyphenyl α-D-glucopyranoside. Its structure features a hydroquinone backbone linked to glucose via an α-glycosidic bond, which enhances stability and reduces potential irritation compared to its β-isomer. This unique configuration allows it to act as a potent inhibitor of tyrosinase, the key enzyme in melanin synthesis.

Commercially, Alpha-Arbutin is produced through enzymatic synthesis, yielding a high-purity grade suitable for cosmetic and pharmaceutical applications. It is commonly standardized to ≥99% purity and is favored in formulations targeting hyperpigmentation, such as skin brightening creams and serums. Its water solubility and compatibility with various ingredients make it a versatile choice for formulators.

In research, Alpha-Arbutin is studied for its efficacy in reducing melanin production, with clinical evidence supporting its use in treating melasma and age spots. As a milder alternative to hydroquinone, it aligns with the growing demand for safe, effective skin-lightening agents.

Structure chimique et propriétés

Alpha-Arbutin is a white crystalline powder with a molecular weight of 272.25 g/mol. It is highly soluble in water and ethanol, facilitating incorporation into aqueous formulations. The α-glycosidic bond is resistant to hydrolysis, ensuring stability in cosmetic products. Its log P is approximately -1.5, indicating hydrophilic nature.

Mécanisme d'action

• Inhibition de la tyrosinase: Competitively inhibits tyrosinase, reducing melanin synthesis.
• Melanin suppression: Decreases melanin content in melanocytes without cytotoxicity.
• Activité antioxydante: Scavenges free radicals, protecting skin from oxidative stress.
• Stabilité: α-glycosidic bond resists enzymatic degradation, prolonging efficacy.

Quality Specifications (QC Tests)

Approvisionnement et documentation

• Capacité: 5 MT/month
• Délai de livraison: 3 à 5 jours ouvrés (articles en stock)
• Documentation: COA, MSDS, TDS
• Emballage: 1 kg, 5 kg, 25 kg

Foire aux questions

What is the MOQ?

Our minimum order quantity is 1 kg. For larger quantities, please contact us for pricing.

What is the delivery time?

For stock items, delivery time is 3-5 business days after order confirmation.

Do you provide samples and COA?

Yes, we provide samples for quality evaluation and a COA for each batch. Please contact us for details.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.