| Nombre del producto | Clorhidrato de berberina |
|---|---|
| Número CAS | 633-65-8 |
| Fórmula molecular | C₂₀H₁₈ClNO₄ |
| Peso molecular | 371.81 g/mol |
| Número EINECS | 211-195-9 |
| Apariencia | Yellow crystalline powder |
| Ensayo (HPLC) | ≥ 98,01 TP3T |
| Pérdida por secado | ≤ 1,01 TP3T |
| Residuo tras la combustión | ≤ 0,51 TP3T |
| Metales pesados | ≤ 10 ppm |
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Clorhidrato de berberina, Berberine HCl, Berberine Chloride Hydrochloride, Natural Yellow 18, C.I. 75160, Umbellatine Hydrochloride
Berberine Hydrochloride is the hydrochloride salt form of berberine, a naturally occurring isoquinoline alkaloid found in several medicinal plants, including Coptis chinensis (Chinese goldthread), Hydrastis canadensis (goldenseal), Berberis aristata (tree turmeric), and Phellodendron amurense (Amur cork tree).
It has been a cornerstone of Traditional Chinese Medicine (TCM) and Ayurvedic medicine for centuries, valued for its broad-spectrum antimicrobial and anti-inflammatory properties.

BERBERINE-HYDROCHLORIDE-N-HYDRATE
In recent decades, berberine has attracted significant scientific attention for its diverse pharmacological activities, particularly its ability to activate AMP-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis. This mechanism underpins its potential in metabolic health, glucose and lipid metabolism, and cardiovascular support.
Berberine is one of the most extensively studied natural alkaloids, with hundreds of clinical trials investigating its efficacy in various conditions.
Berberine hydrochloride is the preferred form for supplementation and research due to its enhanced stability and consistent bioavailability compared to other berberine salts or extracts.
AMPK activator: Activates the master metabolic regulator, promoting glucose uptake and fatty acid oxidation.
Metabolic support: Improves insulin sensitivity and lipid profile.
Actividad antimicrobiana: Broad-spectrum activity against bacteria, fungi, and protozoa.
Anti-inflammatory effects: Modulates inflammatory pathways, including NF-κB.
Actividad antioxidante: Scavenges reactive oxygen species (ROS).
Apoyo cardiovascular: Supports healthy cholesterol levels and vascular function.
Fuente: Coptis chinensis (Chinese goldthread), Hydrastis canadensis (goldenseal), Berberis aristata
Normalización: ≥98.0% berberine hydrochloride (HPLC)
Formularios: Yellow crystalline powder (pharmaceutical-grade and research-grade available)
Aplicaciones: Dietary supplements, pharmaceutical research, and traditional medicine formulations
| Parámetro | Especificaciones |
|---|---|
| Berberine Hydrochloride Content (HPLC) | ≥ 98,01 TP3T |
| Identificación | El espectro UV-Vis/IR se ajusta a la referencia |
| Punto de fusión | 204 – 206°C (with decomposition) |
| Pérdida por secado | ≤ 1,01 TP3T |
| Residuo tras la combustión | ≤ 0,51 TP3T |
| Chloride Content | 9.0 – 10.0% |
| Metales pesados (expresados en Pb) | ≤ 10 ppm |
| Arsénico (As) | ≤ 1 ppm |
| Microbial Limits | Conforms to USP/EP standards |
Capacidad mensual: 1,000+ kg
Plazo de entrega: 3-5 días (muestras), 10-15 días (a granel)
Documentación: COA, TDS,
Embalaje: 1 kg, 5 kg, 10 kg, 25 kg (double‑layer PE bag inside, fiber drum outside)
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