Tranexamic Acid

What is Tranexamic Acid?

Tranexamic acid (TXA) is a synthetic analog of the amino acid lysine. It exerts its effects by reversibly blocking plasminogen binding to fibrin, thereby inhibiting fibrinolysis (blood clot breakdown). This mechanism makes it valuable in both medical and cosmetic applications.

In recent years, tranexamic acid has gained significant traction in the cosmeceutical industry as a topical and injectable agent for treating hyperpigmentation disorders, including melasma, post-inflammatory hyperpigmentation (PIH), and UV-induced dark spots.

Anwendungen

1. Medical – Hemostasis
Heavy menstrual bleeding (HMB) – Reduces blood loss by stabilizing clots
Post-surgical bleeding – Used in cardiac surgery, dental extraction, and trauma
Epistaxis – Nasal bleeding control
Hereditary angioedema – Reduces attack frequency
2. Cosmetic – Skin Brightening & Anti-Pigmentation
Tranexamic acid is now a gold standard ingredient in depigmenting formulations due to its ability to:

1. Inhibit the plasmin/plasminogen pathway – Reduces melanocyte activation by inflammatory mediators (prostaglandins, arachidonic acid)
2. Block UV-induced melanogenesis – Prevents pigmentation without the irritation of hydroquinone
3. Reduce erythema and vascularity – Improves skin tone uniformity

Common formulation types:

Topical serums / creams (2–5%)

1. Mesotherapy solutions
2. Oral tablets (250–500 mg) for resistant melasma
3. Mechanism of Action (MOA) – Skin Lightening

Quality Specifications for B2B Buyers

1. Assay (HPLC): 99.0% – 101.0%
2. Appearance: White or almost white crystalline powder
3. Melting Point : 218 – 222°C
4. Loss on Drying : ≤ 0.5%

Advantages of Sourcing from LyvBio Co., Ltd.

At LyvBio Co., Ltd. , we provide tranexamic acid with:

Traceable supply chain – GMP-compliant manufacturing facilities
Full documentation – COA, MSDS, MOA, flow chart, stability data
Third-party testing – Purity, heavy metals, residual solvents, microbials
Flexible packaging – 1kg, 5kg, 25kg, or custom drums
Lead time – Samples: 3–5 days; Bulk orders: 10–15 days (1kg – 1,000kg+)

Technische FAQs

Q: What is the recommended oral dosage for melasma?
A: Clinical studies typically use 250–500 mg twice daily for 8–12 weeks. We recommend consulting a physician.

Q: Can tranexamic acid be used with hydroquinone?
A: Yes. TXA is often combined with low-dose hydroquinone and a retinoid to reduce irritation while enhancing efficacy.

Q: Is your tranexamic acid vegan/cruelty-free?
A: Yes. Our TXA is synthetically produced, contains no animal-derived materials, and is not tested on animals.

F: Wie hoch ist Ihre Mindestbestellmenge?
A: 1kg for sample orders. Volume discounts available for 25kg+.