Ibuprofen

Synonyme: 2-(4-Isobutylphenyl)propionic acid, p-Isobutylhydratropic acid, (±)-Ibuprofen, Advil, Motrin, Brufen, Nuprin, 15687-27-1

Ibuprofen is a propionic acid derivative and one of the most widely used nonsteroidal anti-inflammatory drugs (NSAIDs) in the world. First synthesized by Boots in the 1960s, it remains a staple in both prescription and over-the-counter medicine for its reliable analgesic, antipyretic, and anti-inflammatory effects. The compound is a racemic mixture of two enantiomers, with the S(+)-form responsible for the majority of its pharmacological activity.

Chemically, ibuprofen is a small lipophilic molecule that acts by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing prostaglandin synthesis. Its relatively simple structure and well-characterized safety profile have made it a benchmark NSAID for pain and inflammation management, from headaches and dental pain to arthritis and soft tissue injuries.

For pharmaceutical manufacturers, ibuprofen is supplied as a high-purity active pharmaceutical ingredient (API) that meets current pharmacopeial monographs (USP/EP/BP). It is available in various particle sizes and grades to suit different formulation needs, including immediate-release tablets, suspensions, and topical gels. Our material is produced under cGMP conditions and comes with full regulatory documentation to support your product development and commercial production.

Function & Mechanism

• COX inhibition: Reversibly inhibits cyclooxygenase-1 and -2, reducing prostaglandin synthesis and thereby lowering pain, fever, and inflammation.
• Analgesic effect: Effective against mild to moderate pain, including headache, dental, and musculoskeletal pain.
• Antipyretic action: Acts on the hypothalamus to reset the body’s temperature set point during fever.
• Anti-inflammatory activity: Reduces swelling and joint stiffness, particularly useful in arthritis and soft tissue injuries.
• Platelet function: Reversibly inhibits platelet aggregation, but with shorter duration than aspirin.

Source & Standardization

• Quelle: Synthetic chemical synthesis
• Manufacturing: Produced via a multi-step organic synthesis process under cGMP conditions
• Standardization: Complies with USP, EP, and BP monographs; assay 99.0–101.0% (on dried basis)
• Forms: White to off-white crystalline powder; various particle size grades available
• Anwendungen: Solid dosage forms (tablets, capsules), oral suspensions, topical gels and creams, and veterinary products

Quality Specifications (QC Tests)

Bulk Supply & Documentation

• Monthly capacity: 50 metric tons
• Lieferzeit: 3–5 Werktage (Lagerware)
• Dokumentation: COA, MSDS, TDS, and regulatory support (DMF) available upon request
• Verpackung: 25 kg fiber drum with double polyethylene liner; custom packaging available

Häufig gestellte Fragen

What is the minimum order quantity (MOQ) for Ibuprofen?

Our standard MOQ is 25 kg, but we can accommodate smaller quantities for trial or research purposes. Please contact us for specific requirements.

How long does delivery take?

For stock items, delivery is typically 3-5 business days after order confirmation. We ship worldwide with reliable logistics partners.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, we provide a COA for each batch. Samples are available upon request for qualified customers, typically shipped within 1-2 days.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.