Dihydroavenanthramide D (Alcohol-Soluble)

Synonyme: Dihydroavenanthramide D, DHAvD, Avenanthramide D reduced, 2-[(2E)-3-(4-Hydroxy-3-methoxyphenyl)prop-2-enoylamino]-5-hydroxybenzoic acid

In the personal care industry, formulators are constantly seeking multifunctional actives that can address both skin soothing and anti-aging claims. Dihydroavenanthramide D has emerged as a standout ingredient in this space, particularly for products targeting sensitive or reactive skin. Its popularity stems from a unique dual mechanism: it mimics the body’s natural anti-inflammatory pathways while also providing antioxidant protection. This makes it a go-to for high-end serums, moisturizers, and after-sun care, where it can replace or complement traditional soothing agents like bisabolol or panthenol.

Dihydroavenanthramide D is a synthetic analog of avenanthramides, the bioactive compounds found in oats (Avena sativa). While natural avenanthramides are a mixture of several cinnamoyl anthranilic acid derivatives, this particular molecule is the reduced form of avenanthramide D, where the double bond in the side chain is saturated. This structural modification enhances stability and skin penetration. The alcohol-soluble grade is specifically designed for use in ethanol-based or glycol-containing formulations, offering excellent compatibility with a wide range of cosmetic solvents.

Our Dihydroavenanthramide D is produced via a proprietary synthetic route that ensures high purity (≥98% by HPLC) and consistent quality. It is standardized as a single, well-characterized entity, free from the batch-to-batch variability often seen in botanical extracts. This makes it ideal for brands that require precise dosing and reproducible efficacy. Whether you’re developing a calming toner or a protective day cream, this ingredient delivers reliable performance without the regulatory complexities associated with novel compounds.

Produktübersicht und Zusammensetzung

Chemically, Dihydroavenanthramide D is a cinnamoyl anthranilic acid derivative with a molecular formula of C17H15NO6 and a molecular weight of 329.30 g/mol. It features a 4-hydroxy-3-methoxyphenyl (ferulic acid-like) moiety linked via an amide bond to a 5-hydroxyanthranilic acid. The reduction of the double bond in the side chain (compared to the natural avenanthramide D) results in a more flexible molecule that can better interact with biological targets. The alcohol-soluble grade is typically supplied as a fine powder that dissolves readily in ethanol, propylene glycol, and other common cosmetic alcohols, making it easy to incorporate into anhydrous or low-water formulations.

Our product is synthesized under cGMP-like conditions and undergoes rigorous purification to remove residual solvents and impurities. Each batch is tested for assay, solubility, and heavy metals to ensure it meets the stringent requirements of the personal care industry. The alcohol-soluble form is particularly valued for its compatibility with ethanol-based systems, where it remains stable and does not recrystallize.

Wichtigste Anwendungsbereiche

• Soothing and anti-redness products: Dihydroavenanthramide D is highly effective at reducing skin redness and irritation. It works by inhibiting the release of pro-inflammatory cytokines and modulating neurogenic inflammation, making it ideal for products aimed at sensitive or rosacea-prone skin.
• Anti-aging and antioxidant serums: As a potent antioxidant, it scavenges free radicals and protects against UV-induced oxidative stress. It also helps to maintain skin barrier function, reducing the appearance of fine lines and wrinkles.
• After-sun and post-procedure care: Its calming properties make it a perfect fit for after-sun lotions, aftershave balms, and post-procedure creams, where it can quickly alleviate discomfort and promote recovery.
• Hair and scalp care: The ingredient can be incorporated into scalp treatments to soothe irritation and reduce flaking, thanks to its anti-inflammatory action.
• Oral care: Emerging research suggests potential benefits in oral care products for reducing gum inflammation, though this is still a niche application.

Qualität und Standards

Verpackung und Beschaffung

• Verpackung: 1 kg, 5 kg, 25 kg fiber drums with double polyethylene liners. Custom packaging available upon request.
• Mindestbestellmenge: 1 kg
• Lieferzeit: 3–5 Werktage (Lagerware)
• Dokumentation: COA, MSDS, TDS, and allergen statement provided with each shipment.

Angebotsanfrage

• LyvBio GmbH. — E-Mail: info@lyvbio.com