L-Leucine

L-Leucine

Produktname L-Leucine
CAS-Nummer 61-90-5
Aussehen White crystalline powder or colorless crystals
Technische Daten USP/EP/AJI
Assay 98.5% – 101.5% (dry basis)
Molekülformel C6H13NO2
Molekulargewicht 131.17 g/mol
Löslichkeit Slightly soluble in water (22.4 g/L at 20°C), practically insoluble in ethanol
Verpackung 25 kg fiber drum or paper bag with inner PE liner

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L-Leucine Structure

Synonyme: L-Leucine, (S)-2-Amino-4-methylpentanoic acid, L-2-Amino-4-methylpentanoic acid, (S)-Leucine, 2-Amino-4-methylpentanoic acid, L-α-Aminoisocaproic acid

L-Leucine is one of the three branched-chain amino acids (BCAAs) and is widely used in pharmaceutical formulations, clinical nutrition, and sports supplements. Its role in muscle protein synthesis and metabolic regulation has made it a key ingredient in parenteral nutrition solutions and performance products.

As an essential amino acid, L-Leucine cannot be synthesized by the human body and must be obtained from dietary sources. It is commercially produced through microbial fermentation or enzymatic resolution, yielding high-purity material suitable for injectable and oral applications.

Our L-Leucine is available in USP, EP, and AJI grades, with strict control over optical purity and endotoxin levels. It is supplied as a white crystalline powder, free from animal-derived components and suitable for vegetarian and halal formulations.

Produktübersicht und Zusammensetzung

L-Leucine is a non-polar, aliphatic amino acid that plays a critical role in protein synthesis and energy metabolism. It is the most potent of the BCAAs in stimulating muscle protein synthesis, primarily through activation of the mTOR signaling pathway.

In pharmaceutical and nutraceutical applications, L-Leucine is often combined with isoleucine and valine in a 2:1:1 ratio, or used alone in specialized formulas targeting muscle wasting, hepatic encephalopathy, and metabolic support.

Wichtigste Anwendungsbereiche

  • Pharmaceutical formulations: used in parenteral and enteral nutrition, as well as in oral supplements for muscle wasting and metabolic disorders.
  • Sports nutrition: included in BCAA and pre-workout products to support muscle recovery and endurance.
  • Clinical nutrition: added to amino acid solutions for patients with hepatic impairment or trauma.
  • Food and beverage: used as a flavor enhancer and nutritional fortifier in functional foods.
  • Cell culture media: essential component in biopharmaceutical manufacturing and research.

Qualität und Standards

Parameter Technische Daten
Assay (dry basis) 98.5% – 101.5%
Specific Rotation +14.5° to +16.5° (dry basis)
Trocknungsverlust ≤ 0.2%
Verbrennungsrückstand ≤ 0.1%
Schwermetalle ≤ 10 ppm
Microbial Limits Total aerobic count ≤ 1000 CFU/g; Yeast & Mold ≤ 100 CFU/g; E. coli absent
Endotoxin ≤ 0.1 EU/mg (for injectable grade)

Verpackung und Beschaffung

  • Verpackung: 25 kg fiber drums with double polyethylene liners, or 25 kg paper bags for solid dosage applications.
  • Mindestbestellmenge: 25 kg (1 drum)
  • Lieferzeit: 3–5 Werktage (Lagerware)
  • Dokumentation: COA, MSDS, TDS, nutritional analysis, and regulatory support available upon request.

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