Salidroside

Salidroside

Product Name Salidroside
CAS Number 10338-51-9
Molecular Formula C₁₄H₂₀O₇
Molecular Weight 300.30 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥ 98.0%
Solubility Slightly soluble in methanol (trace), pyridine (trace)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Melting Point 158 – 160°C
Specific Rotation -28.0° to -32.0°

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Salidroside (98% Purity)

Synonyms: Salidroside, Rhodioloside, Rhodosin, (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol, 4-Hydroxyphenethyl β-D-glucopyranoside, Glucosyltyrosol, Tyrosol Glucoside, p‑Hydroxyphenethyl β‑D‑glucopyranoside—-Rhodiola Rosea Extract

Salidroside, also known as rhodioloside, is a naturally occurring phenylpropanoid glycoside and the primary active marker of Rhodiola rosea (Arctic Root). It is structurally composed of a β‑D‑glucose moiety linked to tyrosol (p‑hydroxyphenethyl alcohol). This compound is one of the key bioactive constituents responsible for Rhodiola’s adaptogenic and pharmacological properties.

Salidroside has been extensively studied for its adaptogenic, neuroprotective, antioxidant, and anti‑fatigue effects. It acts through multiple pathways, including the activation of AMPK and modulation of neurotransmitter systems (serotonin, dopamine, and norepinephrine), contributing to its ability to enhance stress resilience, cognitive function, and physical performance.

As a pure compound, Salidroside is widely used as a reference standard and research reagent in pharmacological studies, as well as a high‑grade ingredient in premium dietary supplements targeting mental and physical vitality.

buy Salidroside

C14H20O7

Function

  • Adaptogenic activity: Enhances stress resistance and reduces fatigue.

  • Neuroprotective support: Protects neurons from oxidative damage and promotes cognitive function.

  • Antioxidant activity: Scavenges free radicals, upregulates endogenous antioxidant enzymes.

  • Anti‑fatigue effect: Supports energy metabolism, reduces exercise‑induced exhaustion.

  • Mood support: Modulates neurotransmitter balance (serotonin, dopamine, norepinephrine).

  • Cardiovascular protection: Supports vascular health through antioxidant and anti‑inflammatory actions.

Source & Purity

  • Source: Rhodiola rosea L. root and rhizome (extraction and purification) or synthetic production

  • Standardization: ≥98.0% salidroside (HPLC)

  • Forms: White to off‑white crystalline powder

  • Applications: Research, dietary supplements, reference standards, premium formulations

Specifications

Parameter Specification
Salidroside Content (HPLC) ≥ 98.0%
Identification IR / MS / NMR conforms to reference
Specific Rotation -28.0° to -32.0°
Melting Point 158 – 160°C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm
Arsenic (As) ≤ 1 ppm
Microbial Limits Conforms to USP/EP standards
Residual Solvents Meets USP requirements

Documentation & Supply

  • Monthly capacity: 50+ kg

  • Lead time: 3–5 days (samples), 10–15 days (bulk)

  • Documentation: COA, MSDS

  • Packaging: 1 kg, 5 kg, 10 kg, 25 kg

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