| Product Name | Matrine |
|---|---|
| CAS Number | 519-02-8 |
| Molecular Formula | C₁₅H₂₄N₂O |
| Molecular Weight | 248.36 g/mol |
| EINECS Number | 610-750-6 |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥ 99.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
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Matrine is a naturally occurring quinolizidine alkaloid extracted primarily from the roots of Sophora flavescens (Kushen) and other Sophora species.
It is one of the major bioactive constituents of the plant and has been extensively studied for its broad spectrum of pharmacological activities, including anti-inflammatory, antiviral, antifungal, and insecticidal properties.
In traditional Chinese medicine, matrine-containing herbs have been used for centuries to treat conditions such as jaundice, dysentery, and skin disorders.
Matrine is widely utilized in pharmaceutical research, veterinary medicine, agricultural biopesticides, and as a reference standard in analytical chemistry.
Matrine
Synonyms: Matridin-15-one, Sophocarpidine, α-Matrine, (+)-Matrine, NSC 146461
Source: Extraction from Sophora flavescens root (botanical origin)
Standardization: ≥99.0% Matrine (HPLC)
Forms: Crystalline powder (pharmaceutical-grade and research-grade available)
Applications: Pharmaceutical R&D, API intermediate, veterinary medicine, botanical pesticide, analytical reference standards
| Compound | Purity | CAS No. | Key Application | Relationship |
|---|---|---|---|---|
| Matrine | ≥99% | 519-02-8 | Pharmaceutical R&D / Biopesticide | Parent compound |
| Oxymatrine | ≥98% | 16837-52-8 | Anti-inflammatory / Antiviral | N-oxide derivative |
| Sophocarpine | ≥98% | 6483-15-4 | Anticancer research | Structural analogue |
| Sophoridine | ≥98% | 6882-68-4 | Cardiovascular research | Stereoisomer |
| Parameter | Specification |
|---|---|
| Matrine Content (HPLC) | ≥ 99.0% |
| Identification | HPLC retention time |
| Specific Rotation [α]₂₀ | +39.0° to +44.0° (c=1, H₂O) |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
| Arsenic (As) | ≤ 1 ppm |
| Purity (by HPLC) | ≥ 99.0% |
Monthly capacity: 100+ kg
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS
Packaging: 1 kg, 5 kg, 10 kg, 25 kg (double‑layer PE bag inside, fiber drum outside)
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