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Red Clover Extract
| Product Name | Red Clover Extract |
|---|---|
| CAS Number | N/A (botanical extract) |
| Appearance | Brown to dark brown fine powder |
| Active Components | Isoflavones (Formononetin, Biochanin A, Genistein, Daidzein) |
| Assay (HPLC) | Isoflavones: 8% – 40% (per grade) |
| Loss on Drying | ≤ 5.0% |
| Residue on Ignition | ≤ 8.0% |
| Heavy Metals | ≤ 10 ppm |
| Particle Size | 100% through 80 mesh |
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Synonyms: Red Clover Extract, Red Clover Isoflavones, Trifolium pratense Extract, Red Clover Herb Extract, Red Clover Flower Extract, Red Axle Extract, Red Axle Isoflavone, Trifolium Extract, Clover Isoflavones
Red Clover Extract is a standardized botanical concentrate derived from the dried flowers and leaves of Trifolium pratense, a perennial herbaceous plant native to Europe, Asia, and North America. It has been traditionally used in herbal medicine for its phytoestrogenic, anti-inflammatory, and blood-purifying properties. Red clover is one of the richest natural sources of isoflavones, a class of plant-derived phytoestrogens that structurally resemble human estrogen.
The primary bioactive isoflavones in red clover include formononetin, biochanin A, genistein, and daidzein. These compounds exhibit estrogenic and anti-estrogenic activities, making red clover extract a popular ingredient in formulations targeting menopausal health, bone health, and cardiovascular support. The isoflavones also possess antioxidant and anti-inflammatory properties.
Red Clover Extract is widely used in dietary supplements, functional foods, and research applications for women’s health, hormonal balance, and overall wellness.

Trifolium pratense Extract
Phytoestrogenic activity: Provides plant-based estrogenic support, helpful for menopausal symptoms.
Bone health support: Isoflavones contribute to bone density and mineral retention.
Antioxidant activity: Scavenges free radicals, reduces oxidative stress.
Cardiovascular support: Supports healthy lipid metabolism and vascular function.
Anti-inflammatory activity: Reduces inflammatory markers and cytokine production.
Source: Dried flowers and leaves of Trifolium pratense
Extraction: Hydroalcoholic extraction, followed by concentration and drying
Standardization: Isoflavones (HPLC)
| Grade | Total Isoflavones (HPLC) | Typical Use |
|---|---|---|
| 8% | ≥8.0% | Standard supplements, cost‑effective formulations |
| 20% | ≥20.0% | High‑potency women’s health supplements |
| 40% | ≥40.0% | Premium formulations, research |

| Application Area | Typical Dosage (as extract) | Rationale |
|---|---|---|
| Menopausal support (hot flashes) | 40 – 80 mg/day (isoflavones) | Phytoestrogenic modulation |
| Bone health | 40 – 80 mg/day (isoflavones) | Bone density support |
| Cardiovascular health | 40 – 80 mg/day (isoflavones) | Lipid metabolism support |
| Antioxidant support | 40 – 80 mg/day (isoflavones) | Oxidative stress reduction |
Monthly capacity: 2,000+ kg
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS, stability data (upon request)
Packaging: 1 kg, 5 kg, 10 kg, 25 kg
Q: What is the difference between red clover extract and soy isoflavones?
A: Both are rich in isoflavones, but red clover contains a different isoflavone profile, with higher levels of formononetin and biochanin A, while soy is higher in genistein and daidzein.
Q: What is the recommended dosage for menopausal support?
A: Clinical studies typically use 40 – 80 mg of total isoflavones per day, often standardized to 20% isoflavones.
Q: Is red clover extract suitable for vegetarians and vegans?
A: Yes, it is plant-derived and suitable for vegetarian and vegan applications.
Q: Does red clover extract interact with medications?
A: Red clover may interact with hormone therapy, blood thinners, and medications metabolized by the liver. Consult a healthcare professional before use.
Q: Is red clover extract suitable for long-term use?
A: Red clover extract is generally considered safe for short- to medium-term use. Long-term use should be monitored by a healthcare professional.
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