Benflumetol

Benflumetol

Product Name Benflumetol
CAS Number 82186-77-4
Molecular Formula C30H32Cl3NO
Molecular Weight 528.94
Appearance White to slightly yellow crystalline powder
Assay (HPLC) ≥98%
Melting Point 130–134 °C
Solubility Soluble in dichloromethane, chloroform; slightly soluble in ethanol
Loss on Drying ≤0.5%
Heavy Metals ≤10 ppm

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Benflumetol Structure

Benflumetol (lumefantrine) is a synthetic arylamino alcohol antimalarial, structurally related to quinine and mefloquine. It acts by inhibiting heme polymerization within the parasite’s digestive vacuole, leading to parasite death. Supplied as a white to slightly yellow crystalline powder with ≥98% purity by HPLC, it is the standard partner drug in artemisinin-based combination therapies (ACTs), most notably with artemether.

This product is intended for pharmaceutical formulation and research use. Each batch is released with a certificate of analysis, and documentation is available to support regulatory submissions.

Synonyms: Lumefantrine, Benflumetol, (±)-2,7-Dichloro-α-(2-(dibutylamino)ethyl)-9-((4-chlorophenyl)methylene)-9H-fluorene-4-methanol, CP-15,456, Benflumetol (INN)

Applications

  • Active pharmaceutical ingredient (API) for antimalarial drug formulations, particularly in combination with artemether for uncomplicated Plasmodium falciparum malaria
  • Research and development in tropical medicine and parasitology
  • Reference standard for analytical method development and quality control

Quality & Documentation

Every batch is tested for assay (HPLC ≥98%), loss on drying (≤0.5%), heavy metals (≤10 ppm), and residual solvents per ICH guidelines. A full COA, MSDS, and TDS are provided with shipment; stability data and impurity profiles are available on request for qualification.

Packaging & Supply

Standard packaging: 1 kg, 5 kg, 25 kg; custom packing and bulk quantities available. In-stock items ship within 3–5 business days; MOQ from 1 kg. For pricing, samples, or technical questions, contact our sales team.

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  • Our Address: 280 Main Street, Xian, Shaanxi, China
  • LyvBio Co., Ltd. — Email: info@lyvbio.com

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