Palmitoyl Hexapeptide-12

Palmitoyl Hexapeptide-12

Product Name Palmitoyl Hexapeptide-12
CAS Number 171263-26-6
Other Names Palmitoyl Hexapeptide-12, Palmitoyl Hexapeptide-12 Acetate, C16-Hexapeptide-12
Molecular Formula C42H80N12O9
Molecular Weight 897.18 g/mol
Appearance White to off-white powder
Assay (HPLC) ≥95.0%
Loss on Drying ≤5.0%
Residue on Ignition ≤1.0%
Heavy Metals ≤10 ppm
Solubility Soluble in water, ethanol, and propylene glycol
Particle Size 95% pass through 80 mesh
Package 1 kg, 5 kg in aluminum foil bags; 25 kg in fiber drums

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Palmitoyl Hexapeptide-12 Structure

Synonyms: Palmitoyl Hexapeptide-12, Palmitoyl Hexapeptide-12 Acetate, C16-Hexapeptide-12, N-Palmitoyl Hexapeptide-12

Palmitoyl Hexapeptide-12 is a synthetic lipopeptide consisting of six amino acids linked to palmitic acid (C16). This molecule belongs to the class of signal peptides, which are designed to mimic the body’s natural peptide signals to stimulate collagen production and improve skin firmness. It is widely used in high-end anti-aging skincare formulations.

Chemically, Palmitoyl Hexapeptide-12 is a derivative of the natural hexapeptide sequence that corresponds to a fragment of the human collagen type I propeptide. The palmitoyl chain enhances lipophilicity, allowing better penetration through the stratum corneum. This peptide has been shown to upregulate collagen synthesis and downregulate collagenase activity, leading to improved skin elasticity and reduced wrinkle depth.

Our Palmitoyl Hexapeptide-12 is produced through solid-phase peptide synthesis and purified by HPLC to ensure high purity and consistent quality. It is available as a white powder with ≥95% assay, suitable for use in cosmetic formulations targeting anti-aging, firming, and repair. The product is supplied with comprehensive documentation, including COA and MSDS, and is manufactured under strict quality control to meet the demands of the personal care industry.

Function

  • Collagen stimulation: Promotes collagen I, III, and IV synthesis, improving skin firmness and elasticity.
  • Anti-wrinkle: Reduces the appearance of fine lines and wrinkles by enhancing extracellular matrix production.
  • Skin repair: Accelerates wound healing and improves skin barrier function.
  • Moisturizing: Enhances skin hydration by supporting hyaluronic acid synthesis.
  • Anti-inflammatory: Modulates inflammatory responses, soothing irritated skin.

Source & Standardization

  • Source: Synthetic peptide produced by solid-phase peptide synthesis.
  • Extraction: Not applicable; chemically synthesized.
  • Standardization: ≥95.0% (HPLC).
  • Forms: White to off-white powder.
  • Applications: Anti-aging creams, serums, eye care products, and other cosmetic formulations.

Specifications

Parameter Specification
Assay (HPLC) ≥95.0%
Identification Matches reference standard
Loss on Drying ≤5.0%
Residue on Ignition ≤1.0%
Heavy Metals ≤10 ppm
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent

Documentation & Supply

  • Monthly capacity: 50 kg
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request
  • Packaging: 1 kg, 5 kg in aluminum foil bags; 25 kg in fiber drums

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