Nonapeptide-1

Nonapeptide-1

Product Name Nonapeptide-1
CAS Number 158563-45-2
Synonyms Melanostatine-5, Nonapeptide-1, Nona-peptide-1
Molecular Formula C61H87N15O9S2
Molecular Weight 1286.6 g/mol
Appearance White to off-white powder
Purity ≥98% (HPLC)
Solubility Soluble in water and polar organic solvents
Storage Store at -20°C, protect from light and moisture

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Nonapeptide-1 Structure

Synonyms: Melanostatine-5, Nonapeptide-1, Nona-peptide-1, Melanostatin-5, N-Acetyl-Nonapeptide-1

Nonapeptide-1 is a synthetic peptide composed of nine amino acids, designed to mimic the natural regulatory peptide melanostatin. It acts as a potent antagonist of the melanocortin-1 receptor (MC1R), thereby inhibiting melanin synthesis. This mechanism makes it a valuable active ingredient for skin-lightening and hyperpigmentation treatments.

As a cosmetic peptide, Nonapeptide-1 is widely used in advanced skincare formulations targeting age spots, melasma, and uneven skin tone. It is also employed in research settings to study melanogenesis and pigmentation disorders. The peptide is typically produced via solid-phase peptide synthesis and is available in high purity grades suitable for both cosmetic and research applications.

Product Highlights

  • High purity: ≥98% as determined by HPLC, ensuring consistent performance.
  • Clinically studied: Shown to reduce melanin production in vitro and in vivo.
  • Versatile: Compatible with a wide range of cosmetic formulations.
  • Regulatory support: Manufactured under cGMP conditions, with full documentation.
  • Scalable supply: Bulk quantities available for commercial production.
  • Expert support: Technical assistance for formulation and regulatory needs.

Applications

  • Skin-lightening creams and serums
  • Anti-aging and brightening skincare products
  • Treatment of hyperpigmentation (e.g., melasma, age spots)
  • Research on melanogenesis and melanocortin receptors
  • Cosmetic formulations for even skin tone

Specifications

Parameter Specification
Appearance White to off-white powder
Purity (HPLC) ≥98%
Molecular Weight 1286.6 g/mol
Solubility Soluble in water
Storage -20°C, protected from light
Standard In-house

Ordering & Supply

  • Packaging: 1 g, 10 g, 100 g, or bulk quantities in amber glass vials or aluminum foil bags.
  • MOQ: 1 gram.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request.
  • Shipping: Shipped at ambient temperature or with dry ice upon request.

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