Taurocholic Acid

Synonyms: Taurocholic acid, TCA, Cholyltaurine, 2-[(3α,5β,7α,12α)-3,7,12-Trihydroxy-24-oxocholan-24-yl]aminoethanesulfonic acid, N-Choloyltaurine, Taurocholate

Taurocholic acid has become a molecule of intense interest across the pharmaceutical and nutraceutical sectors, driven by the growing demand for bile acid derivatives in drug delivery and metabolic health. As a key component of bile, it is increasingly sought after for its role in enhancing the bioavailability of poorly soluble drugs and as a critical raw material in the synthesis of advanced therapeutic agents. Its unique surface-active properties make it indispensable in formulations targeting lipid absorption and liver function.

Chemically, taurocholic acid is a bile acid conjugated with taurine, belonging to the family of taurine-conjugated bile acids. It is one of the major bile acids in humans and is produced in the liver from cholesterol. In its pure form, it appears as a white to off-white crystalline powder, highly soluble in water, which distinguishes it from many other bile acids. This water solubility is a significant advantage in aqueous formulations and biotechnological applications.

LyvBio offers taurocholic acid with a guaranteed purity of ≥98% (HPLC), meeting the stringent requirements of pharmaceutical and research applications. Our product is manufactured under cGMP conditions, ensuring consistent quality and regulatory compliance. Whether you are developing a novel drug delivery system or conducting metabolic studies, our taurocholic acid provides the reliability and performance your projects demand.

Product Overview & Composition

Taurocholic acid is a primary bile acid that plays a crucial role in the emulsification and absorption of dietary fats. Its molecular structure comprises a steroid nucleus with three hydroxyl groups and a taurine moiety, which confers high water solubility and surface activity. This amphiphilic nature allows it to form micelles, enhancing the solubilization of lipophilic compounds.

In the pharmaceutical industry, taurocholic acid is employed as a permeation enhancer and as a building block for the synthesis of other bile acid derivatives. Its ability to modulate drug transport across biological membranes makes it valuable in oral and topical formulations. Additionally, it serves as a reference standard in analytical methods for bile acid profiling.

Key Applications

• Pharmaceutical excipient: Used as a solubilizing agent to improve the bioavailability of poorly water-soluble drugs.
• Drug delivery systems: Enhances intestinal absorption of peptides and other macromolecules.
• Research and diagnostics: Serves as a standard for bile acid analysis and in studies of lipid metabolism.
• Nutraceuticals: Incorporated into supplements aimed at supporting liver health and fat digestion.
• Biotechnology: Utilized in cell culture media and protein stabilization.

Quality & Standards

Packaging & Supply

• Packaging: 25 kg fiber drum with double polyethylene liner, or as per customer request.
• MOQ: 1 kg
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS available upon request.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com