Vitamin K2 MK-7 (Menaquinone-7) is the most bioavailable and longest-acting form of vitamin K2, belonging to the menaquinone family. It is naturally produced by bacterial fermentation and is found in fermented foods such as natto, a traditional Japanese soybean product. MK-7 is distinguished from other vitamin K forms by its longer isoprenoid side chain, which confers superior absorption, extended half-life, and more sustained tissue distribution.

Vitamin K2 serves as an essential cofactor for γ-glutamyl carboxylase, an enzyme responsible for the post-translational carboxylation of specific glutamic acid residues in vitamin K-dependent proteins (VKDPs). These include osteocalcin (involved in bone mineralization) and matrix Gla protein (MGP, a potent inhibitor of vascular calcification). By activating these proteins, vitamin K2 plays a critical role in calcium homeostasis, directing calcium into bone tissue while preventing its deposition in arterial walls.

MK-7 is the preferred form for supplementation due to its once-daily dosing convenience, superior bioavailability, and proven efficacy in clinical studies. It is widely used in bone health, cardiovascular health, and healthy aging formulations.

機能：

• Superior bioavailability: Longer side chain enhances absorption and tissue distribution.

• Extended half-life: Approximately 72 hours, supporting once-daily dosing.

• Bone health: Activates osteocalcin, promoting bone mineralization.

• Cardiovascular protection: Activates MGP, inhibiting arterial calcification.

• Synergistic with vitamin D3: Cooperates in calcium trafficking and utilization.

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