パルミトイルトリペプチド-1

Synonyms: Palmitoyl Tripeptide-1, Pal-GHK, Palmitoyl-Gly-His-Lys, N-Palmitoyl-Glycyl-L-histidyl-L-lysine

In the crowded field of anti-aging actives, Palmitoyl Tripeptide-1 has carved out a reputation as a dependable workhorse. It shows up in premium serums, eye creams, and treatment masks, often paired with other peptides or growth factors. Formulators reach for it because it targets visible signs of aging without the irritation that retinol or high-dose acids can bring. The molecule itself is a lipophilic derivative of the naturally occurring tripeptide GHK, where a palmitic acid chain is attached to the N-terminus. This clever modification enhances its ability to penetrate the stratum corneum, making it far more bioavailable than its unmodified counterpart.

Palmitoyl Tripeptide-1 (CAS 147732-56-7) is a synthetic peptide that signals the skin to ramp up collagen production, improve elasticity, and support the extracellular matrix. It works by mimicking the natural breakdown products of collagen, which triggers fibroblasts to synthesize new collagen fibers. Over time, this leads to a visible reduction in fine lines and wrinkles, firmer skin, and a more even texture. It is often called a ‘matrix peptide’ because it helps rebuild the skin’s structural framework.

Our Palmitoyl Tripeptide-1 is synthesized via solid-phase peptide synthesis and purified to ≥98% (HPLC). It is a fine white powder that is readily soluble in water, making it easy to incorporate into a wide range of cosmetic formulations. With a low molecular weight of 673.97 g/mol, it penetrates efficiently into the skin. Each batch is rigorously tested to ensure purity, heavy metal content, and microbial safety, meeting the highest standards for cosmetic ingredients.

Product Overview & Composition

Palmitoyl Tripeptide-1 is a synthetic peptide composed of three amino acids: glycine, histidine, and lysine, with a palmitic acid moiety attached to the glycine residue. The palmitoyl group is a 16-carbon saturated fatty acid that increases the lipophilicity of the peptide, facilitating its absorption through the lipid-rich outer layer of the skin. This structure is designed to mimic the natural peptide fragments that result from collagen breakdown, which serve as signals for the skin to initiate repair and regeneration.

The peptide is stable and compatible with a variety of cosmetic ingredients, including emulsifiers, thickeners, and other peptides. It is typically used at concentrations between 1-5% in leave-on products, though lower levels are effective in rinse-off formulations. Its activity is enhanced when combined with other matrix peptides like Palmitoyl Tetrapeptide-7, with which it is often blended to address multiple signs of aging simultaneously.

Key Applications

• Anti-aging creams and serums: Stimulates collagen synthesis, reducing fine lines and wrinkles.
• Eye care products: Helps firm the delicate under-eye area, diminishing puffiness and dark circles.
• Facial masks and ampoules: Provides intensive treatment for mature or stressed skin.
• Body lotions and firming creams: Improves skin elasticity and tone.
• Sun care aftercare: Supports skin repair after UV exposure.
• Scalp and hair products: May support hair follicle health and thickness.

Quality & Standards

包装・供給

• パッケージ: 1kg, 5kg, 25kg fiber drums with double PE bags inside.
• 最小発注数量（MOQ）: 5g
• リードタイム: 3-5 days for stock; 15-20 days for custom synthesis.
• ドキュメント: COA, MSDS, TDS, and allergen statement available upon request.

見積依頼

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