Ubiquinol (Reduced Coenzyme Q10)

Synonyms: Reduced Coenzyme Q10, Ubiquinol-10, CoQ10H2, Dihydrocoenzyme Q10, Reduced CoQ10, Ubiquinol

Ubiquinol is the reduced, active form of coenzyme Q10 (CoQ10), a fat-soluble benzoquinone derivative that plays a central role in cellular energy production. While CoQ10 exists in two forms—ubiquinone (oxidized) and ubiquinol (reduced)—it is ubiquinol that serves as the primary electron carrier in the mitochondrial respiratory chain and as a potent lipid-soluble antioxidant. In the human body, ubiquinol is the dominant form circulating in plasma, but its levels decline with age and in certain health conditions, making supplementation a topic of significant interest in clinical nutrition.

First identified in 1957, coenzyme Q10 has since been the subject of thousands of studies, yet ubiquinol specifically gained commercial attention in the early 2000s when efficient stabilization and production methods were developed. Unlike ubiquinone, which requires enzymatic conversion in the body, ubiquinol is directly bioavailable, a characteristic that appeals to formulators targeting older adults or individuals with compromised conversion capacity. Our ubiquinol is produced via microbial fermentation followed by a proprietary reduction process, ensuring high purity and consistent isomeric configuration.

As a bulk ingredient, ubiquinol is standardized to ≥98.0% by HPLC, with strict control over residual solvents, heavy metals, and microbial contamination. It is supplied as a crystalline powder with a melting point around 45–48°C, and is typically formulated into softgel capsules, oil suspensions, or functional beverages. The ingredient is widely used in dietary supplements aimed at cardiovascular support, energy enhancement, and antioxidant defense, as well as in cosmetic and pharmaceutical research.

機能

• Mitochondrial energy production: Ubiquinol acts as an electron carrier in the electron transport chain, facilitating ATP synthesis.
• Antioxidant protection: It neutralizes lipid peroxyl radicals, protecting cell membranes and LDL cholesterol from oxidative damage.
• Cardiovascular support: Supports endothelial function and maintains healthy blood pressure and heart muscle energetics.
• 神経保護: May help reduce oxidative stress in neuronal cells, supporting cognitive health.
• Skin health: Used in anti-aging formulations for its ability to protect against UV-induced oxidative stress.

Source & Standardization

• 出典: Microbial fermentation (e.g., Agrobacterium tumefaciens or Rhodobacter sphaeroides) followed by chemical reduction.
• Extraction: Fermentation broth is harvested, cells disrupted, and ubiquinol isolated via solvent extraction and chromatography.
• Standardization: ≥98.0% ubiquinol (HPLC), with ≤0.5% ubiquinone as related substance.
• Forms: White to off-white crystalline powder, typically stabilized with antioxidants such as vitamin E or ascorbyl palmitate.
• 用途: Dietary supplements (softgels, capsules), functional foods, beverages, cosmetics, and pharmaceutical research.

仕様

資料・供給

• 月間処理能力: 500 kg
• リードタイム: 3～5営業日（在庫品）
• ドキュメント: COA, MSDS, TDS, and regulatory support available upon request.
• パッケージ: 1 kg, 5 kg, 25 kg net weight in aluminum foil bags or fiber drums, with nitrogen flushing for stability.

見積依頼

• リブバイオ株式会社. — メールアドレス： info@lyvbio.com