Thiamine nitrate

Thiamine nitrate

Produktname Thiamine nitrate
Andere Bezeichnungen Vitamin B1 nitrate, Thiamine mononitrate, Aneurine nitrate
CAS-Nummer 532-43-4
Molekülformel C12H17N5O4S
Molekulargewicht 327.36 g/mol
Aussehen Weißes bis cremefarbenes kristallines Pulver
Assay 98.0% – 101.0% (on dried basis)
Trocknungsverlust ≤ 1,01 TP3T
Verbrennungsrückstand ≤ 0.1%
pH (2% solution) 6.5 – 7.5
Schwermetalle ≤ 10 ppm
Löslichkeit Soluble in water (~1 g/10 mL), slightly soluble in ethanol
Verpackung 25 kg fiber drum with double polyethylene liner

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Thiamine nitrate Structure

Synonyms: Thiamine mononitrate, Vitamin B1 nitrate, Aneurine nitrate, 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium nitrate

Thiamine nitrate is the nitrate salt form of thiamine (vitamin B1), a water-soluble vitamin essential for carbohydrate metabolism and neural function. It is produced synthetically and supplied as a white to off-white crystalline powder with a characteristic faint odor. Unlike thiamine hydrochloride, the nitrate salt is less hygroscopic and exhibits greater stability in dry blends, making it a preferred choice for certain solid dosage forms and food fortification.

As a vitamin B1 source, thiamine nitrate is widely used in pharmaceutical preparations, dietary supplements, and food enrichment. It plays a critical role in energy production as a coenzyme in the citric acid cycle and pentose phosphate pathway. The nitrate form is particularly valued in multivitamin tablets and premixes where moisture sensitivity is a concern.

Product Highlights

  • High purity: ≥98.0% assay, meeting USP/EP/BP standards.
  • Low hygroscopicity: More stable than thiamine hydrochloride in solid formulations.
  • Regulatory compliance: Produced in cGMP-compliant facilities, suitable for pharmaceutical and food applications.
  • Consistent supply: Large-scale production capacity ensures reliable lead times.
  • Comprehensive documentation: COA, MSDS, TDS, and regulatory support available.
  • Versatile applications: Suitable for tablets, capsules, powders, and liquid formulations.

Anwendungen

  • Pharmaceutical preparations for thiamine deficiency and beriberi.
  • Dietary supplements and multivitamin formulations.
  • Food fortification (e.g., cereals, flour, infant formula).
  • Animal feed additives to prevent thiamine deficiency.
  • Cell culture media and biochemical research.

Technische Daten

Parameter Technische Daten
Assay (on dried basis) 98.0% – 101.0%
Trocknungsverlust ≤ 1,01 TP3T
Verbrennungsrückstand ≤ 0.1%
pH (2% solution) 6.5 – 7.5
Schwermetalle ≤ 10 ppm
Aussehen Weißes bis cremefarbenes kristallines Pulver

Ordering & Supply

  • Verpackung: 25 kg fiber drum with double polyethylene liner, or as per customer requirements.
  • Mindestbestellmenge: 25 kg.
  • Lieferzeit: 3–5 Werktage (Lagerware)
  • Dokumentation: COA, MSDS, TDS, and other regulatory documents upon request.

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