Spermidin

Spermidin

Produktname Spermidin
CAS-Nummer 124-20-9
Molekülformel C₇H₁₉N₃
Molekulargewicht 145.25 g/mol
Aussehen Weißes bis cremefarbenes kristallines Pulver
Analyse (HPLC) ≥ 99,01 TP3T
Trocknungsverlust ≤ 1,01 TP3T
Verbrennungsrückstand ≤ 0.1%

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Spermidine is a naturally occurring polyamine compound found in all living organisms, playing an essential role in cellular growth, proliferation, and differentiation.

It is synthesized endogenously from putrescine via the addition of an aminopropyl group derived from decarboxylated S-adenosylmethionine (SAM).

Dietary sources include wheat germ, soybeans, aged cheese, mushrooms, and certain fruits.

  • Autophagy induction: Potent activator of autophagic flux, promoting cellular clearance and renewal.

  • DNA/chromatin stabilization: Binds to nucleic acids, protecting against oxidative damage and maintaining chromatin conformation.

  • Cellular proliferation: Essential polyamine for cell cycle progression and tissue regeneration.

  • Anti-inflammatory potential: Modulates inflammatory signaling pathways.

  • Neuroprotektion: Supports neuronal survival and function via autophagy and anti-apoptotic mechanisms.

Related

Verbundstoff CAS-Nr. Beziehung
Spermidin 124-20-9 Parent polyamine
Spermine 71-44-3 Higher homologue, tetra-amine
Putrescine 110-60-1 Precursor to spermidine
Cadaverine 462-94-2 Related diamine
Agmatine 306-60-5 Decarboxylated arginine, related amine

Technische Daten

Parameter Technische Daten
Purity (HPLC) ≥ 99,01 TP3T
Identification IR / MS spectrum conforms to reference
Trocknungsverlust ≤ 1,01 TP3T
Verbrennungsrückstand ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm
Arsenic (As) ≤ 1 ppm
Microbial Limits Conforms to USP/EP standards
Lösungsmittelrückstände Meets USP requirements

Supply

  • Monthly capacity: 10+ kg

  • Lead time: 3–5 days (samples), 10–15 days (bulk)

  • Documentation: COA, HPLC chromatogram, stability data, NMR (upon request)

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