Morantel

Synonyme: Morantel, Morantel tartrate, 20574-50-9, 1-Methyl-2-(2-thienyl)-1,4,5,6-tetrahydropyrimidine

Morantel is a synthetic anthelmintic agent belonging to the tetrahydropyrimidine class. Structurally, it is a methyl-substituted derivative of pyrantel, featuring a thiophene ring that enhances its lipophilicity and tissue distribution. First developed in the 1960s, morantel has been widely used in veterinary medicine to control gastrointestinal nematodes in livestock, particularly cattle and sheep. Its efficacy against a broad spectrum of parasites, including Haemonchus, Ostertagia, and Trichostrongylus species, has made it a staple in deworming programs.

The compound acts as a nicotinic acetylcholine receptor agonist, causing depolarizing neuromuscular blockade in susceptible parasites. This leads to spastic paralysis and subsequent expulsion of the worms from the host. Morantel is often formulated as a tartrate salt to improve water solubility, which facilitates administration via feed or drinking water. Its pharmacokinetic profile allows for effective concentrations in the gastrointestinal tract, with minimal systemic absorption.

In the pharmaceutical and veterinary industries, morantel is valued for its broad-spectrum activity and favorable safety margin. It is commonly supplied as a high-purity active pharmaceutical ingredient (API) for the production of boluses, suspensions, and premixes. Our morantel is manufactured under strict quality control measures, ensuring consistency and compliance with pharmacopeial standards. It is available for bulk purchase, catering to formulators and distributors worldwide.

Function & Mechanism

• Anthelmintic activity: Acts as a nicotinic acetylcholine receptor agonist, causing paralysis and expulsion of gastrointestinal nematodes.
• Broad-spectrum efficacy: Effective against mature and immature stages of major nematode species in ruminants.
• Rapid action: Induces spastic paralysis within hours of administration, leading to worm expulsion.
• Safety profile: Low toxicity to mammals due to poor systemic absorption and selective action on parasite receptors.
• Formulation versatility: Stable in various dosage forms, including oral suspensions and feed additives.

Source & Standardization

• Quelle: Synthetic chemical synthesis
• Standardization: ≥98.0% (HPLC)
• Forms: White to off-white crystalline powder
• Anwendungen: Veterinary anthelmintic formulations, bulk API for pharmaceutical manufacturing

Quality Specifications (QC Tests)

Bulk Supply & Documentation

• Monthly capacity: 5 metric tons
• Lieferzeit: 3–5 Werktage (Lagerware)
• Dokumentation: COA, MSDS, TDS available upon request
• Verpackung: 25 kg fiber drums with inner polyethylene liners

Häufig gestellte Fragen

What is the minimum order quantity (MOQ)?

Our MOQ for morantel is 1 kg. For larger quantities, please contact us for pricing and availability.

What is the delivery time?

For stock items, delivery time is 3-5 business days after order confirmation.

Do you provide samples and COA?

Yes, we can provide samples for quality evaluation. A COA is available for each batch. Please contact us with your specific requirements.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.