Acetyl Tetrapeptide-11

Synonyme: Acetyl Tetrapeptide-11, N-Acetyl-L-alanyl-L-prolyl-L-valyl-L-histidine, Acetyl-Ala-Pro-Val-His, Acetyl Tetrapeptide-11 (INCI)

Acetyl Tetrapeptide-11 is a synthetic tetrapeptide with the sequence N-acetyl-alanyl-prolyl-valyl-histidine. The N-terminal acetyl group protects the peptide from enzymatic degradation, enhancing its stability and bioavailability in topical formulations. This modification is common in cosmeceutical peptides, allowing them to remain active on the skin for longer periods.

Unlike natural peptides that often suffer from rapid breakdown, Acetyl Tetrapeptide-11 is designed for robustness. It belongs to a class of biomimetic peptides that mimic natural growth factors or signaling molecules. The histidine residue contributes to its buffering capacity and potential metal-binding properties, while the alanine and valine residues provide hydrophobic characteristics that influence its interaction with lipid bilayers.

In the personal care industry, Acetyl Tetrapeptide-11 is primarily used as an anti-aging active. It is incorporated into skincare products targeting firmness, elasticity, and overall skin tone. The peptide works by supporting the skin’s natural repair mechanisms, particularly by stimulating collagen synthesis and protecting against glycation, a process that stiffens skin proteins and leads to visible signs of aging.

Our Acetyl Tetrapeptide-11 is manufactured using solid-phase peptide synthesis (SPPS) and purified via preparative HPLC to achieve high purity. It is supplied as a white to off-white powder, readily soluble in water and ethanol, making it suitable for a variety of cosmetic formulations, including serums, creams, and lotions. Each batch is tested for identity, purity, and residual solvents to ensure consistent performance.

Funktion

• Collagen stimulation: Promotes collagen I and III synthesis, improving skin firmness and reducing wrinkles.
• Anti-glycation: Inhibits the formation of advanced glycation end-products (AGEs), protecting skin proteins from cross-linking.
• Skin repair: Enhances keratinocyte proliferation and migration, supporting the skin barrier.
• Antioxidant activity: Scavenges free radicals, reducing oxidative stress in skin cells.
• Anti-inflammatory: Modulates inflammatory cytokines, soothing irritated skin.

Source & Standardization

• Quelle: Synthetic peptide produced by solid-phase peptide synthesis.
• Extraction: Not applicable; chemically synthesized.
• Standardization: ≥98.0% (HPLC).
• Forms: White to off-white powder.
• Anwendungen: Anti-aging serums, creams, lotions, eye care products.

Technische Daten

Documentation & Supply

• Monthly capacity: 50 kg
• Lieferzeit: 3–5 Werktage (Lagerware)
• Dokumentation: COA, MSDS, TDS available upon request
• Verpackung: 1 kg, 5 kg, 10 kg in double PE bags inside fiber drums

Angebotsanfrage

• LyvBio GmbH. — E-Mail: info@lyvbio.com