Livagen

Synonyms: Livagen peptide, Lys-Glu-Asp-Ala, KEDA peptide, Livagen (synthetic tetrapeptide), CAS 195875-61-1

As the global nutraceutical and pharmaceutical industries shift toward precision-based interventions, peptide ingredients with well-defined mechanisms are drawing serious attention. Livagen has become a sought-after building block for formulators developing products aimed at liver support, epigenetic regulation, and healthy aging. Unlike broad-spectrum botanicals, this short synthetic peptide offers a clear molecular target and reproducible activity, making it a favorite among R&D teams in both supplement and clinical research settings.

Chemically, Livagen is a synthetic tetrapeptide with the sequence Lys-Glu-Asp-Ala (KEDA). It belongs to a class of short peptides developed through research into peptide bioregulators—compounds that interact with DNA and modulate gene expression. The sequence is not found intact in dietary proteins; it is produced via solid-phase peptide synthesis and supplied as a lyophilized powder. Its small size (approximately 798 Da) allows for efficient tissue penetration, a property that has sparked interest in its potential to influence liver cell function and systemic regulatory pathways.

Commercial Livagen is typically standardized to ≥98% purity by HPLC, with strict control over residual solvents, counterions, and microbial content. This level of purity is critical for both in vitro studies and finished products where consistency matters. Whether you are formulating a liver-support supplement, a research reagent, or a next-generation anti-aging capsule, Livagen delivers the reliability and traceability that B2B buyers expect.

Product Overview & Composition

Livagen is a linear tetrapeptide composed of L-lysine, L-glutamic acid, L-aspartic acid, and L-alanine. The presence of charged residues (Lys, Glu, Asp) makes the molecule highly polar and water-soluble, while the alanine residue contributes to structural stability. It is synthesized using Fmoc solid-phase chemistry, followed by cleavage and reverse-phase HPLC purification. The final product is usually supplied as the acetate salt to improve solubility and handling.

Each batch is characterized by mass spectrometry and amino acid analysis to confirm sequence integrity. The peptide is hygroscopic and should be stored desiccated at -20°C to maintain long-term stability. For formulation, it can be dissolved in sterile water or buffer, but care should be taken to avoid repeated freeze-thaw cycles.

Key Applications

• Liver health supplements: Livagen is incorporated into capsules and powders targeting hepatic function and detoxification pathways.
• Anti-aging and longevity products: Its potential to modulate gene expression makes it a candidate for epigenetic-focused formulations.
• Research reagents: Used in cell culture and animal studies exploring peptide regulation of liver-specific genes.
• Cosmeceuticals: Emerging interest in topical applications for skin remodeling and cellular renewal.
• Nutraceutical blends: Combined with other bioregulator peptides for synergistic effects in specialized supplements.

Quality & Standards

Packaging & Supply

• Packaging: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg in amber glass vials with rubber stoppers and aluminum seals.
• MOQ: 10 mg (flexible for R&D quantities).
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS, and analytical chromatograms provided with each shipment.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com