Gabapentin

Synonyms

Neurontin, Gabarone, Aclonium, Fanatrex, Gabapentinum, 1-(aminomethyl)cyclohexaneacetic acid, 2-(1-(aminomethyl)cyclohexyl)acetic acid

Gabapentin is a pharmaceutical compound that belongs to the class of gabapentinoids. It is a structural analogue of the neurotransmitter gamma-aminobutyric acid (GABA), yet it does not bind to GABA receptors or influence GABA metabolism. Instead, it interacts with the α2δ subunit of voltage-gated calcium channels, modulating calcium influx and subsequently reducing the release of excitatory neurotransmitters. This mechanism underlies its therapeutic effects in neuropathic pain and epilepsy.

Originally developed as an anticonvulsant, gabapentin is now widely prescribed for a range of conditions, including partial seizures, postherpetic neuralgia, and fibromyalgia. Its favorable safety profile and low potential for drug interactions make it a valuable option in chronic pain management. In addition, it is increasingly used off-label for anxiety disorders, restless legs syndrome, and migraine prophylaxis.

Function

• Anticonvulsant: Gabapentin is effective as adjunctive therapy for partial seizures with or without secondary generalization in adults and children.
• Neuropathic Pain Relief: It is approved for the management of postherpetic neuralgia and is commonly used for diabetic neuropathy and other neuropathic pain conditions.
• Anxiolytic Effects: By modulating calcium channels, it may reduce neuronal excitability and provide relief in generalized anxiety disorder and social anxiety disorder.
• Sleep Modulation: It can improve sleep quality in patients with insomnia, particularly when associated with chronic pain or fibromyalgia.

Source & Purity

• Source: Synthetic compound produced via chemical synthesis.
• Standardization: Meets USP specifications, with purity ≥ 99% as determined by HPLC.
• Forms: Available as bulk powder, capsules, and tablets; also supplied as an active pharmaceutical ingredient (API) for formulation.
• Applications: Used in the manufacture of pharmaceutical dosage forms for oral administration.

Documentation & Supply

• Documentation: COA, MSDS, TDS
• Lead time: 7-15 days after order confirmation, depending on quantity and destination.
• Packaging: Supplied in double polyethylene bags inside fiber drums or as per customer requirement.

Request For Quote

• Our Address: 280 Main Street, Xian, Shaanxi, China
• LyvBio Co., Ltd.
• Email: info@lyvbio.com