| Product Name | Evodiamine |
|---|---|
| CAS Number | 518-17-2 |
| Molecular Formula | C₁₉H₁₇N₃O |
| Molecular Weight | 303.36 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥ 98.0% |
| Evodia Extract (10:1): | Brown fine powder |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Melting Point | 263 – 265°C |
| Specific Rotation | +350° to +360° |
| Particle Size | 100% through 80 mesh |
Need help? Contact our team
Evodiamine is a naturally occurring bioactive alkaloid isolated from the dried unripe fruits of Evodia rutaecarpa (also known as Tetradium ruticarpum), a plant widely used in Traditional Chinese Medicine (TCM) for its digestive and analgesic properties. It belongs to the quinazolinocarboline alkaloid class and is one of the primary active constituents responsible for the pharmacological effects of Evodia fruit.

Medicinal Evodia P.E
Evodiamine has attracted significant scientific interest for its diverse biological activities, including weight management, thermogenesis enhancement, and anti-inflammatory effects. Its mechanism of action involves the activation of TRPV1 (transient receptor potential vanilloid 1), which leads to increased energy expenditure, thermogenesis, and reduced appetite. This unique mechanism has made evodiamine a popular ingredient in weight management supplements.
Additionally, evodiamine exhibits anti-inflammatory, analgesic, and antioxidant properties, making it a subject of research in pain management and neuroprotection.
Thermogenesis promotion: Activates TRPV1, increasing energy expenditure and heat production.
Weight management support: Reduces body fat accumulation and appetite.
Anti-inflammatory activity: Modulates inflammatory pathways, including COX‑2 and NF‑κB.
Analgesic effects: Provides pain relief through capsaicin‑like mechanisms.
Gastrointestinal support: Enhances digestive function and motility.
Antioxidant activity: Scavenges free radicals and reduces oxidative stress.

Evodiamine 98% off-yellow powder : Evodia Extract (10:1): brwon powder
Source: Dried unripe fruits of Evodia rutaecarpa (Tetradium ruticarpum)
Standardization: ≥98.0% evodiamine (HPLC)
Forms: White to off-white crystalline powder (pure compound); also available as standardized extract (e.g., 10:1 extract containing evodiamine)
Applications: Weight management supplements, pain relief formulations, digestive support, anti‑aging products, and research studies
Monthly capacity: Pure Evodiamine (≥98%): 10+ kg; Evodia Extract (10:1): 1,000+ kg
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS, TDS, HPLC chromatogram, stability data, NMR (upon request)
Packaging: Pure Evodiamine: 1 kg, 5 kg, 10 kg, 25 kg; Extract: 1 kg, 5 kg, 10 kg, 25 kg
280 Main Street, Xian, Shaanxi, China
LyvBio Co., Ltd.
Email: info@lyvbio.com
Room,5-0203, Courtyard 205, Lianhu District,Xi'an,Shaanxi,China