Manganese gluconate

Synonyms: Manganese Gluconate, Manganese(II) gluconate, Gluconic acid manganese salt, Manganese D-gluconate, C12H22MnO14, CAS 6485-39-8

Manganese gluconate is the manganese salt of gluconic acid, a mild chelate that pairs the essential trace mineral with a sugar acid naturally found in fruits and honey. The compound appears as a light pink to off-white powder and is prized for its high water solubility, which allows formulators to achieve clear, stable solutions without the precipitation issues common to many inorganic manganese sources.

Chemically, the molecule consists of one manganese(II) ion coordinated with two gluconate moieties, giving a molecular weight of 445.24 g/mol and a manganese content of roughly 11.5–12.5%. This structure places it alongside other mineral gluconates—such as zinc gluconate and ferrous gluconate—that are widely used in clinical nutrition and dietary supplements. Unlike manganese sulfate, which can be irritative and less bioavailable, manganese gluconate is gentle on the gastrointestinal tract and is well tolerated in both oral and topical applications.

In the pharmaceutical and nutraceutical industries, manganese gluconate is standardized to a defined manganese assay and is typically produced under GMP conditions to ensure consistent particle size, low heavy metal content, and microbiological safety. It serves as a key ingredient in multivitamin/mineral tablets, bone health formulas, and parenteral nutrition solutions, where precise dosing and compatibility with other nutrients are critical.

Function

• Essential trace mineral: Supplies manganese for normal bone development, amino acid metabolism, and cholesterol synthesis.
• Enzyme cofactor: Activates manganese superoxide dismutase (MnSOD) and other metalloenzymes involved in antioxidant defense.
• Bone & connective tissue support: Contributes to glycosaminoglycan and collagen formation, aiding joint and cartilage health.
• Metabolic regulation: Plays a role in glucose homeostasis and lipid metabolism.
• Well-tolerated source: Offers high bioavailability with minimal gastric irritation compared to inorganic salts.

Source & Standardization

• Source: Synthetic chelation of manganese carbonate or manganese sulfate with gluconic acid.
• Production: Controlled reaction, purification, spray drying, and milling to achieve a fine, free-flowing powder.
• Standardization: Assay as Mn 11.5–12.5% (dry basis), tested by complexometric titration or atomic absorption spectroscopy.
• Forms: Light pink to off-white crystalline powder; also available as granules or aqueous solution upon request.
• Applications: Dietary supplements, pharmaceutical tablets/capsules, parenteral nutrition, food fortification, and cosmetic formulations.

Specifications

Documentation & Supply

• Monthly capacity: 20 metric tons
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS, GMP certificate, and nutritional analysis available upon request.
• Packaging: 25 kg fiber drums with double polyethylene liners; custom packaging for small-scale trials.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com