L-Threonine

L-Threonine

Product Name L-Threonine
CAS Number 72-19-5
Molecular Formula C4H9NO3
Molecular Weight 119.12 g/mol
Appearance White crystalline powder
Assay (HPLC) 98.5% – 101.5%
Specific Rotation −27.5° to −29.0° (c=6, H2O)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Solubility Soluble in water; slightly soluble in ethanol

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L-Threonine Structure

Synonyms: L-Threonine, (2S,3R)-2-Amino-3-hydroxybutanoic acid, L-α-Amino-β-hydroxybutyric acid, Threonine

L-Threonine is a proteinogenic amino acid with the chemical formula C4H9NO3 and a molecular weight of 119.12 g/mol. As an essential amino acid, it cannot be synthesized by the human body and must be obtained through diet or supplementation. It is one of the three major limiting amino acids in cereal proteins, alongside lysine and methionine.

In the pharmaceutical and nutraceutical industries, L-Threonine is valued for its role in protein synthesis, immune function, and gastrointestinal health. It is also a key component in total parenteral nutrition (TPN) solutions and is used as a precursor in the production of antibiotics and other bioactive compounds. Its versatility extends to animal feed, where it improves growth performance and reduces nitrogen excretion.

Product Highlights

  • High Purity: Assay 98.5%–101.5% (HPLC), meeting USP/EP/AJI standards.
  • Fermentation-Derived: Produced via microbial fermentation, ensuring consistent quality and sustainability.
  • Regulatory Compliance: Manufactured in ISO 9001 and FSSC 22000 certified facilities; Kosher and Halal available.
  • Global Supply: Annual capacity exceeding 10,000 metric tons, with stable supply chains.
  • Technical Support: Comprehensive documentation and regulatory assistance for product registration.

Applications

  • Pharmaceutical formulations: TPN solutions, amino acid infusions, and tablet excipients.
  • Nutraceuticals: sports nutrition, immune support, and digestive health supplements.
  • Animal nutrition: feed additive for swine and poultry to optimize growth.
  • Biotechnology: fermentation media component and precursor for antibiotics.
  • Food and beverage: flavor enhancer and nutritional fortifier.

Specifications

Parameter Specification
Appearance White crystalline powder
Assay (HPLC) 98.5% – 101.5%
Specific Rotation −27.5° to −29.0°
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Solubility Soluble in water

Ordering & Supply

  • Packaging: 25 kg net weight in fiber drums with double polyethylene liners, or as per customer requirements.
  • MOQ: 1,000 kg.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS, and regulatory support (USP/EP/AJI) available upon request.

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