Genistein

Genistein is a naturally occurring isoflavone found primarily in soybeans and other leguminous plants. It is one of the most extensively studied phytoestrogens, recognized for its structural similarity to 17β-estradiol, which enables it to bind to estrogen receptors (ERα and ERβ) and exert both estrogenic and anti-estrogenic effects depending on the tissue and hormonal environment.

In addition to its role in dietary supplements, genistein is widely used as a reference standard in analytical chemistry and as a research tool in molecular biology.

Its safety profile and well-documented bioactivities make it a valuable ingredient in products targeting menopausal health, bone density support, and overall wellness.

genistein sophora japonica fruit powder

Genistein

Caragana sinica-Genistein

Function

• Phytoestrogen: Binds to estrogen receptors, modulating hormonal activity.

• Tyrosine kinase inhibitor: Inhibits EGFR and other receptor tyrosine kinases.

• Antioxidant activity: Activates Nrf2/ARE pathway, scavenges ROS.

• Anti-inflammatory effect: Suppresses NF-κB and pro-inflammatory cytokine production.

• Bone health support: Promotes osteoblast differentiation and inhibits osteoclast activity.

• Cardiovascular protection: Improves endothelial function and lipid metabolism.

Source & Purity

• Source: Soybean (Caragana sinica) extract, or synthetic

• Standardization: ≥98.0% genistein (HPLC)

• Forms: Crystalline powder (natural or synthetic origin)

• Applications: Dietary supplements, pharmaceutical research, analytical standards

Spec