Thiamine nitrate

Thiamine nitrate

Product Name Thiamine nitrate
Other Names Vitamin B1 nitrate, Thiamine mononitrate, Aneurine nitrate
CAS Number 532-43-4
Molecular Formula C12H17N5O4S
Molecular Weight 327.36 g/mol
Appearance White to off-white crystalline powder
Assay 98.0% – 101.0% (on dried basis)
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
pH (2% solution) 6.5 – 7.5
Heavy Metals ≤ 10 ppm
Solubility Soluble in water (~1 g/10 mL), slightly soluble in ethanol
Package 25 kg fiber drum with double polyethylene liner

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Thiamine nitrate Structure

Synonyms: Thiamine mononitrate, Vitamin B1 nitrate, Aneurine nitrate, 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium nitrate

Thiamine nitrate is the nitrate salt form of thiamine (vitamin B1), a water-soluble vitamin essential for carbohydrate metabolism and neural function. It is produced synthetically and supplied as a white to off-white crystalline powder with a characteristic faint odor. Unlike thiamine hydrochloride, the nitrate salt is less hygroscopic and exhibits greater stability in dry blends, making it a preferred choice for certain solid dosage forms and food fortification.

As a vitamin B1 source, thiamine nitrate is widely used in pharmaceutical preparations, dietary supplements, and food enrichment. It plays a critical role in energy production as a coenzyme in the citric acid cycle and pentose phosphate pathway. The nitrate form is particularly valued in multivitamin tablets and premixes where moisture sensitivity is a concern.

Product Highlights

  • High purity: ≥98.0% assay, meeting USP/EP/BP standards.
  • Low hygroscopicity: More stable than thiamine hydrochloride in solid formulations.
  • Regulatory compliance: Produced in cGMP-compliant facilities, suitable for pharmaceutical and food applications.
  • Consistent supply: Large-scale production capacity ensures reliable lead times.
  • Comprehensive documentation: COA, MSDS, TDS, and regulatory support available.
  • Versatile applications: Suitable for tablets, capsules, powders, and liquid formulations.

Applications

  • Pharmaceutical preparations for thiamine deficiency and beriberi.
  • Dietary supplements and multivitamin formulations.
  • Food fortification (e.g., cereals, flour, infant formula).
  • Animal feed additives to prevent thiamine deficiency.
  • Cell culture media and biochemical research.

Specifications

Parameter Specification
Assay (on dried basis) 98.0% – 101.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
pH (2% solution) 6.5 – 7.5
Heavy Metals ≤ 10 ppm
Appearance White to off-white crystalline powder

Ordering & Supply

  • Packaging: 25 kg fiber drum with double polyethylene liner, or as per customer requirements.
  • MOQ: 25 kg.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS, and other regulatory documents upon request.

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