Calcium 2-Oxoglutarate (Calcium α-Ketoglutarate) is the calcium salt of α-ketoglutaric acid, a key intermediate in the tricarboxylic acid (TCA) cycle.

This compound integrates the metabolic functions of α-ketoglutarate with the essential mineral calcium, providing a combined approach to cellular energy metabolism and bone health support.

α-Ketoglutarate serves as a critical node in the TCA cycle, linking carbohydrate, amino acid, and fatty acid metabolism. It also functions as a nitrogen scavenger and a precursor for glutamate and glutamine synthesis. In recent years, it has attracted attention for its potential in healthy aging, cellular energy, and amino acid metabolism applications.

Calcium 2-oxoglutarate

Function

• TCA cycle intermediate: Directly participates in cellular energy production.

• Nitrogen metabolism: Acts as a nitrogen sink and supports ammonia detoxification.

• Amino acid precursor: Serves as a precursor to glutamate and glutamine.

• Mineral supply: Provides bioavailable calcium for bone and skeletal health.

• Stability: Calcium salt form offers improved handling and shelf stability compared to free acid.

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