Seladelpar

Synonyms: MBX-8025, RWJ-800025, 2-[(4-{[(2R)-2-ethoxy-3-[4-(trifluoromethyl)phenoxy]propyl]sulfanyl}phenyl)carbamoyl]cyclopropane-1-carboxylic acid

Seladelpar is a synthetic, orally active small molecule developed as a selective peroxisome proliferator-activated receptor delta (PPARδ) agonist. It belongs to the class of cyclopropanecarboxylic acid derivatives and is manufactured under cGMP conditions to high purity, typically ≥98% by HPLC.

As a research-grade API, Seladelpar is used by pharmaceutical and biotech companies for preclinical and clinical studies targeting metabolic and cholestatic liver diseases. Its high selectivity for PPARδ over PPARα and PPARγ makes it a valuable tool for investigating lipid metabolism, inflammation, and bile acid homeostasis.

Product Highlights

• High purity: ≥98% by HPLC, suitable for in vitro and in vivo studies.
• Selective PPARδ agonist: >1000-fold selectivity over PPARα and PPARγ.
• GMP-grade manufacturing: Produced under strict quality control for consistent batch-to-batch performance.
• Regulatory support: Comprehensive documentation including COA, MSDS, and TDS.
• Scalable supply: Available from milligrams to grams to support early development.

Applications & Formulation Use

• Preclinical research on non-alcoholic steatohepatitis (NASH) and primary biliary cholangitis (PBC).
• Study of lipid metabolism and insulin sensitivity.
• Investigation of anti-inflammatory pathways in liver and metabolic tissues.
• Formulation development for oral solid dosage forms.

Quality Specifications (QC Tests)

Bulk Supply & Ordering

• Packaging: Amber glass vials or double-lined aluminum pouches.
• MOQ: 10 mg (stock items); custom quantities available.
• Lead time: 3-5 business days (stock items).
• Documentation: COA, MSDS, TDS provided with each shipment.

Frequently Asked Questions

What is the minimum order quantity (MOQ) for Seladelpar?

Our standard MOQ is 10 mg for stock items. Larger quantities can be accommodated upon request.

What is the delivery time?

For stock items, delivery is 3-5 business days from order confirmation.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, a COA is provided with every order. Samples are available upon request for qualified customers.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.