Eprinomectin

Synonyms: Eprinomectin, MK-397, 4”-epi-acetylamino-4”-deoxy-avermectin B1, Eprinex, Ivomec Eprinex, LongRange

Eprinomectin has become a preferred macrocyclic lactone for formulators targeting both internal and external parasites in livestock, particularly in dairy cattle where zero milk withdrawal is a decisive advantage. As resistance to older avermectins and milbemycins continues to spread, demand for this molecule has grown steadily across the animal health sector, especially in pour-on and injectable product lines.

Chemically, eprinomectin is a semi-synthetic derivative of avermectin B1, modified at the 4”-position of the oleandrose sugar moiety with an epi-acetylamino group. This structural change enhances its potency against a broad spectrum of nematodes and arthropods while maintaining an excellent safety profile in target animals. It is produced via fermentation of Streptomyces avermitilis followed by chemical derivatization.

LyvBio supplies eprinomectin with a minimum assay of 95.0% (HPLC), a standard suitable for veterinary drug manufacturing and research applications. Our material is manufactured under cGMP conditions, ensuring consistent quality and full regulatory documentation for global markets.

Product Overview & Composition

Eprinomectin is a mixture of two homologues, B1a and B1b, typically in a ratio of approximately 90:10. The active ingredient is the 4”-epi-acetylamino derivative, which confers improved antiparasitic activity and a favorable pharmacokinetic profile. The product is supplied as a white to off-white crystalline powder, practically insoluble in water but freely soluble in most organic solvents.

Applications & Product Lines

• Dairy cattle pour-on: For control of gastrointestinal roundworms, lungworms, grubs, lice, and mange mites, with zero milk withdrawal.
• Beef cattle injectables: For treatment and control of internal and external parasites.
• Sheep and goat formulations: Effective against a range of nematodes and ectoparasites.
• Companion animal products: Used in spot-on and oral formulations for dogs and cats.
• Research and reference standards: For analytical method development and quality control.

Quality Control Standards

Bulk Packaging & Supply

• Packaging: 25 kg fiber drum with double polyethylene liner, or as per customer request.
• MOQ: 1 kg for stock items; 25 kg for customized packaging.
• Lead time: 3-5 business days for stock items.
• Documentation: COA, MSDS, TDS, and regulatory support available upon request.

Frequently Asked Questions

What is the minimum order quantity (MOQ) for eprinomectin?

Our MOQ is 1 kg for stock items. For customized packaging or larger quantities, please contact us to discuss your specific requirements.

How long does delivery take?

For stock items, delivery is typically 3-5 business days after order confirmation. We maintain sufficient inventory to ensure prompt shipment.

Can you provide a COA and samples?

Yes, we provide a COA for each batch. Samples are available upon request, usually shipped within 1-2 days.

What packaging options are available?

Standard packaging is 25 kg fiber drums with double polyethylene liners. We can also accommodate custom packaging sizes to meet your production needs.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.