N-Acetyl L-Tyrosine

N-Acetyl L-Tyrosine

Product Name N-Acetyl L-Tyrosine
CAS Number 537-55-3
Synonyms N-Acetyl-L-tyrosine, Acetyl L-tyrosine, L-N-Acetyltyrosine, NAT, N-Acetyl-4-hydroxyphenylalanine
Molecular Formula C11H13NO4
Molecular Weight 223.23 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) 98.0% – 102.0% (dry basis)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Specific Rotation [α]D20 +24° to +27° (c=2, H2O)
Solubility Soluble in water, ethanol; practically insoluble in acetone
Particle Size 100% through 80 mesh
Package 25 kg fiber drum with double polyethylene liner

Need help? Contact our team

N-Acetyl L-Tyrosine Structure

Synonyms: N-Acetyl-L-tyrosine, Acetyl L-tyrosine, L-N-Acetyltyrosine, NAT, N-Acetyl-4-hydroxyphenylalanine

N-Acetyl L-Tyrosine has emerged as a key ingredient in the nootropic and sports nutrition segments, driven by consumer demand for cognitive enhancers and stress-management solutions. Formulators favor it over plain L-tyrosine for its superior water solubility and stability, making it easier to incorporate into capsules, tablets, and functional beverages. As the market for mental performance products expands, this acetylated amino acid continues to gain traction among brands targeting focus, alertness, and resilience under stress.

N-Acetyl L-Tyrosine is the acetylated form of the essential amino acid L-tyrosine, which serves as a direct precursor to the catecholamines dopamine, norepinephrine, and epinephrine. While L-tyrosine itself is poorly soluble, acetylation yields a derivative that dissolves readily in water and resists degradation during processing and storage. This makes it a practical choice for manufacturers seeking a reliable, bioavailable tyrosine source for their formulations.

Our N-Acetyl L-Tyrosine is produced via enzymatic acetylation of L-tyrosine, followed by purification and crystallization. We offer a consistent, high-purity grade (≥98% by HPLC) with low heavy metals and tight particle size control. Each batch is tested for identity, assay, and residual solvents to meet the stringent requirements of dietary supplement and pharmaceutical applications.

Product Overview & Composition

N-Acetyl L-Tyrosine is a white crystalline powder with a molecular weight of 223.23 g/mol. It is chemically stable under normal storage conditions, though it should be protected from moisture and direct light. The compound is freely soluble in water (approximately 10 mg/mL at 25°C), which facilitates uniform dispersion in aqueous systems.

As a derivative of L-tyrosine, it retains the phenolic side chain essential for neurotransmitter synthesis. Upon ingestion, it is rapidly deacetylated to L-tyrosine, ensuring a steady supply of the precursor without the solubility limitations of the parent amino acid.

Key Applications

  • Nootropic supplements: Supports cognitive function, focus, and mental clarity under demanding conditions.
  • Sports nutrition: Helps maintain performance and delay fatigue during prolonged physical exertion.
  • Stress management: Acts as a precursor to catecholamines, which regulate the body’s response to stress.
  • Functional foods and beverages: Water-soluble nature allows easy incorporation into RTD drinks and powders.
  • Pharmaceutical research: Used in studies investigating neurotransmitter modulation and metabolic pathways.

Quality & Standards

Parameter Specification
Assay (HPLC) 98.0% – 102.0%
Loss on Drying ≤ 0.5%
Heavy Metals ≤ 10 ppm
Microbial Limits Total aerobic count ≤ 1000 CFU/g; Yeast & mold ≤ 100 CFU/g; E. coli absent
Residual Solvents Meets USP <467> requirements

Packaging & Supply

  • Packaging: 25 kg fiber drums with double polyethylene liners, or as per customer request.
  • MOQ: 25 kg.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request.

Request For Quote

STAY IN TOUCH

Request For Quote

Our Address

Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

✅ ×