Tauroursodeoxycholic Acid (TUDCA)

Synonyms: TUDCA, Tauroursodeoxycholate, 3α,7β-Dihydroxy-5β-cholanoyltaurine, Ursodeoxycholyltaurine, Tauroursodeoxycholic acid

Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated bile acid that occurs naturally in the bile of bears and, to a lesser extent, humans. It is the taurine conjugate of ursodeoxycholic acid (UDCA), a secondary bile acid with a long history in hepatology. While UDCA itself has been used clinically for decades, TUDCA has emerged as a compound of intense interest due to its superior water solubility and distinct cytoprotective properties. As a research chemical and pharmaceutical intermediate, TUDCA is typically supplied as a white to off-white crystalline powder with a purity of ≥98% (HPLC).

In the B2B arena, TUDCA is valued not only for its role as an active pharmaceutical ingredient (API) in certain markets but also as a key reference standard and intermediate in bile acid chemistry. Its applications span from hepatology research and mitochondrial biology to the development of novel formulations targeting cholestatic liver diseases and neurodegenerative conditions. The global demand for high-purity TUDCA has grown steadily, driven by both clinical research and the nutraceutical sector, where it is incorporated into specialized supplements. LyvBio supplies TUDCA with consistent quality, backed by comprehensive documentation, to meet the rigorous standards of pharmaceutical and research institutions worldwide.

Product Highlights

• High Purity: ≥98% by HPLC, ensuring reliable performance in sensitive applications.
• Regulatory Support: Available with DMF (Drug Master File) support for pharmaceutical customers.
• Scalable Production: Manufactured in quantities from grams to metric tons, with a current annual capacity of 5 MT.
• Quality Assurance: Produced under cGMP conditions; each batch comes with a comprehensive COA.
• Custom Solutions: Custom packaging and labeling available to meet specific client requirements.
• Global Logistics: Efficient worldwide shipping with temperature-controlled options if needed.

Applications

• Pharmaceutical Research: As a reference standard and active in studies of cholestasis, apoptosis, and mitochondrial function.
• Nutraceuticals: Incorporated into liver support and metabolic health supplements.
• Cell Culture: Used as a supplement in cell culture media to reduce endoplasmic reticulum stress.
• Formulation Development: As a solubilizing agent for poorly soluble drugs and as a permeation enhancer.
• Analytical Chemistry: Reference standard for HPLC, LC-MS, and other analytical methods.

Specifications

Ordering & Supply

• Packaging: 25 kg fiber drums with double polyethylene liners; smaller quantities available in amber glass bottles or aluminum foil bags.
• MOQ: 1 kg for standard packaging; custom MOQs negotiable for bulk orders.
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS, and DMF (upon request).
• Storage: Store in a cool, dry place, protected from light and moisture.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com